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    Ccdc13 coiled-coil domain containing 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 686091, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc13provided by RGD
    Official Full Name
    coiled-coil domain containing 13provided by RGD
    Primary source
    RGD:1586605
    See related
    EnsemblRapid:ENSRNOG00000025643 AllianceGenome:RGD:1586605
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in cytoplasmic microtubule organization and non-motile cilium assembly. Predicted to act upstream of or within DNA damage response. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be active in centriolar satellite. Orthologous to human CCDC13 (coiled-coil domain containing 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 68.0), Muscle (RPKM 11.0) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc13 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (130335797..130391658, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (121455202..121507487, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (130436529..130475521, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene kelch-like family member 40 Neighboring gene hedgehog acyltransferase-like Neighboring gene HIG1 hypoxia inducible domain family, member 1A Neighboring gene atypical chemokine receptor 2 Neighboring gene cytochrome P450 family 8 subfamily B member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability. Staples CJ, et al. J Cell Sci, 2014 Jul 1. PMID 24816561
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cytoplasmic microtubule organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in non-motile cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriolar satellite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain containing 13; coiled-coil domain-containing protein 13

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      130335797..130391658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082754.2 → XP_038938682.1  coiled-coil domain-containing protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AFB0
      Conserved Domains (2) summary
      COG1196
      Location:76 → 454
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:339 → 610
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. XM_039082751.2 → XP_038938679.1  coiled-coil domain-containing protein 13 isoform X1

      UniProtKB/TrEMBL
      M0R4S7
      Conserved Domains (2) summary
      COG1196
      Location:76 → 455
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:340 → 611
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. XM_063266488.1 → XP_063122558.1  coiled-coil domain-containing protein 13 isoform X2

      UniProtKB/TrEMBL
      A0A8I6AFB0

    4. XM_039082753.2 → XP_038938681.1  coiled-coil domain-containing protein 13 isoform X1

      UniProtKB/TrEMBL
      M0R4S7
      Related
      ENSRNOP00000093179.2, ENSRNOT00000100163.2
      Conserved Domains (2) summary
      COG1196
      Location:76 → 455
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:340 → 611
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    5. XM_039082755.2 → XP_038938683.1  coiled-coil domain-containing protein 13 isoform X3

      Conserved Domains (2) summary
      COG1196
      Location:76 → 455
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:340 → 611
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    6. XM_063266490.1 → XP_063122560.1  coiled-coil domain-containing protein 13 isoform X5

    7. XM_063266491.1 → XP_063122561.1  coiled-coil domain-containing protein 13 isoform X5

    8. XM_063266489.1 → XP_063122559.1  coiled-coil domain-containing protein 13 isoform X4

    9. XM_063266492.1 → XP_063122562.1  coiled-coil domain-containing protein 13 isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version

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