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    Hdhd3 haloacid dehalogenase-like hydrolase domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688746, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hdhd3provided by RGD
    Official Full Name
    haloacid dehalogenase-like hydrolase domain containing 3provided by RGD
    Primary source
    RGD:1585262
    See related
    EnsemblRapid:ENSRNOG00000064638 AllianceGenome:RGD:1585262
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable hydrolase activity. Predicted to be located in mitochondrion and nucleolus. Predicted to be active in nucleus. Orthologous to human HDHD3 (haloacid dehalogenase like hydrolase domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 382.8), Kidney (RPKM 89.5) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Hdhd3 in Genome Data Viewer
    Location:
    5q24
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (80966878..80970345, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (75951308..75954775, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (78358183..78361650, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547534 Neighboring gene B-box and SPRY domain containing Neighboring gene aminolevulinate dehydratase Neighboring gene DNA polymerase epsilon 3, accessory subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables hydrolase activity  
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle  
    located_in mitochondrion PubMed 
    located_in nucleolus  

    General protein information

    Preferred Names
    haloacid dehalogenase-like hydrolase domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109511.1NP_001102981.1  haloacid dehalogenase-like hydrolase domain-containing protein 3

      See identical proteins and their annotated locations for NP_001102981.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473978
      UniProtKB/TrEMBL
      A0A8I6AQS2, A6J7V3, B2RYT7
      Related
      ENSRNOP00000094317.1, ENSRNOT00000118724.2
      Conserved Domains (1) summary
      TIGR02252
      Location:8210
      DREG-2; REG-2-like, HAD superfamily (subfamily IA) hydrolase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      80966878..80970345 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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