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    Tmed7 transmembrane p24 trafficking protein 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 252889, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmed7provided by RGD
    Official Full Name
    transmembrane p24 trafficking protein 7provided by RGD
    Primary source
    RGD:727954
    See related
    EnsemblRapid:ENSRNOG00000042070 AllianceGenome:RGD:727954
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    p27
    Summary
    Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in bounding membrane of organelle and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to several human genes including TMED7 (transmembrane p24 trafficking protein 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 647.0), Kidney (RPKM 489.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmed7 in Genome Data Viewer
    Location:
    18q11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (41505167..41512243, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (39318564..39325640, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (40579182..40586260, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene fem-1 homolog C Neighboring gene TIR domain containing adaptor molecule 2 Neighboring gene eukaryotic translation initiation factor 1A Neighboring gene 40S ribosomal protein S23-like Neighboring gene cysteine dioxygenase type 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi organization  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport  
    involved_in intracellular protein transport  
    involved_in protein transport  
    Component Evidence Code Pubs
    located_in COPI-coated vesicle membrane  
    is_active_in COPII-coated ER to Golgi transport vesicle  
    located_in ER to Golgi transport vesicle membrane  
    is_active_in Golgi apparatus  
    located_in Golgi apparatus  
    located_in Golgi apparatus  
    located_in Golgi apparatus  
    is_active_in endoplasmic reticulum  
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum membrane  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment  
    located_in endoplasmic reticulum-Golgi intermediate compartment  
    located_in endoplasmic reticulum-Golgi intermediate compartment  
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane  

    General protein information

    Preferred Names
    transmembrane emp24 domain-containing protein 7
    Names
    UV36Sp6 ultraviolet B radiation-activated UV36
    p24 family protein gamma-3
    p24gamma3
    transmembrane emp24 protein transport domain containing 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105758.1NP_001099228.1  transmembrane emp24 domain-containing protein 7 precursor

      See identical proteins and their annotated locations for NP_001099228.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473971
      UniProtKB/Swiss-Prot
      D3ZTX0
      UniProtKB/TrEMBL
      A0A8I6AC82
      Related
      ENSRNOP00000004942.5, ENSRNOT00000004942.7
      Conserved Domains (1) summary
      pfam01105
      Location:38214
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      41505167..41512243 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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