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    Crabp2 cellular retinoic acid binding protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29563, updated on 9-Dec-2024

    Summary

    Symbol
    Crabp2provided by RGD
    Full Name
    cellular retinoic acid binding protein 2provided by RGD
    Primary source
    RGD:62070
    See related
    AllianceGenome:RGD:62070
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables retinoic acid binding activity. Involved in retinoic acid biosynthetic process. Predicted to be located in endoplasmic reticulum and nucleoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human CRABP2 (cellular retinoic acid binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 95.9), Thymus (RPKM 65.6) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Crabp2 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (175714862..175719208)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173417004..173421352)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187322416..187326794)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L24 Neighboring gene methyltransferase like 25B Neighboring gene interferon stimulated exonuclease gene 20-like 2 Neighboring gene nestin Neighboring gene brevican

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cyclin binding  
    enables cyclin binding  
    enables fatty acid binding  
    enables lipid binding PubMed 
    enables retinal binding  
    enables retinoic acid binding  
    enables retinoic acid binding PubMed 
    enables retinoic acid binding  
    enables retinoic acid binding  
    enables retinol binding  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in cytoplasm  
    is_active_in cytosol  
    located_in cytosol  
    located_in cytosol  
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum  
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    cellular retinoic acid-binding protein 2
    Names
    CRABP-II
    cellular lipid-binding protein
    cellular retinoic acid-binding protein 2-like
    cellular retinoic acid-binding protein II

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017244.2 → NP_058940.1  cellular retinoic acid-binding protein 2

      See identical proteins and their annotated locations for NP_058940.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      P51673
      UniProtKB/TrEMBL
      A0A8L2Q848
      Conserved Domains (1) summary
      cl10502
      Location:3 → 139
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      175714862..175719208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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