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    Tceanc2 transcription elongation factor A N-terminal and central domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366431, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tceanc2provided by RGD
    Official Full Name
    transcription elongation factor A N-terminal and central domain containing 2provided by RGD
    Primary source
    RGD:1359481
    See related
    EnsemblRapid:ENSRNOG00000009398 AllianceGenome:RGD:1359481
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TCEANC2 (transcription elongation factor A N-terminal and central domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 62.3), Spleen (RPKM 62.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tceanc2 in Genome Data Viewer
    Location:
    5q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (127152776..127197405, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (121923959..121963018, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (126746165..126782726, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene cytochrome b5 reductase-like Neighboring gene ribosomal protein L28, pseudogene 1 Neighboring gene CUB domain containing protein 2 Neighboring gene transfer RNA alanine (anticodon AGC) 38 Neighboring gene transmembrane protein 59 Neighboring gene low density lipoprotein receptor class A domain containing 1 Neighboring gene leucine rich repeat containing 42 Neighboring gene intraflagellar transport 25

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor A N-terminal and central domain-containing protein 2
    Names
    transcription elongation factor A (SII) N-terminal and central domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014260.2 → NP_001014282.1  transcription elongation factor A N-terminal and central domain-containing protein 2

      See identical proteins and their annotated locations for NP_001014282.1

      Status: VALIDATED

      Source sequence(s)
      AI043997, BC083757, DY316983
      UniProtKB/Swiss-Prot
      Q5XIC7
      UniProtKB/TrEMBL
      A6JYQ7
      Related
      ENSRNOP00000049524.3, ENSRNOT00000048784.5
      Conserved Domains (1) summary
      cd00183
      Location:38 → 111
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      127152776..127197405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039110461.2 → XP_038966389.1  transcription elongation factor A N-terminal and central domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5XIC7
      UniProtKB/TrEMBL
      A6JYQ7
      Conserved Domains (1) summary
      cd00183
      Location:38 → 111
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XIC7.1 GenPept UniProtKB/Swiss-Prot:Q5XIC7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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