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    Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362344, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ndufb2provided by RGD
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit B2provided by RGD
    Primary source
    RGD:1308130
    See related
    EnsemblRapid:ENSRNOG00000084454 AllianceGenome:RGD:1308130
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1710.5), Muscle (RPKM 1698.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ndufb2 in Genome Data Viewer
    Location:
    4q23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (69334307..69341394)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (68367526..68374609)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (67378188..67385267)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene aarF domain containing kinase 2 Neighboring gene thymosin, beta 10, pseudogene 5 Neighboring gene B-Raf proto-oncogene, serine/threonine kinase Neighboring gene ribosomal protein L26, pseudogene 11 Neighboring gene ferritin heavy chain 1, pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in mitochondrial inner membrane  
    located_in mitochondrion PubMed 
    part_of respiratory chain complex I  

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
    NP_001102094.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108624.2 → NP_001102094.2  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

      See identical proteins and their annotated locations for NP_001102094.2

      Status: VALIDATED

      Source sequence(s)
      BC166901, BG668360, C06706
      UniProtKB/TrEMBL
      A6IEV7, B2RYU0, F7F040
      Related
      ENSRNOP00000034770.4, ENSRNOT00000030892.6
      Conserved Domains (1) summary
      pfam14813
      Location:37 → 104
      NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      69334307..69341394
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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