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    Fbxo10 F-box protein 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362511, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fbxo10provided by RGD
    Official Full Name
    F-box protein 10provided by RGD
    Primary source
    RGD:1305465
    See related
    EnsemblRapid:ENSRNOG00000012634 AllianceGenome:RGD:1305465
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in regulation of apoptotic process and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Orthologous to human FBXO10 (F-box protein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 70.3), Uterus (RPKM 24.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fbxo10 in Genome Data Viewer
    Location:
    5q22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (64092709..64139054, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (59297016..59343429, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (60589881..60636551, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486934 Neighboring gene RNA polymerase I subunit E Neighboring gene translocase of outer mitochondrial membrane 5 Neighboring gene ribosomal protein L24-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytoplasm  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427214.1 → NP_001414143.1  F-box only protein 10

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A1B0GWU1, A6IJ84
      Related
      ENSRNOP00000076020.1, ENSRNOT00000093103.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      64092709..64139054 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238142.5 → XP_006238204.1  F-box only protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006238204.1

      Conserved Domains (1) summary
      pfam13229
      Location:273 → 419
      Beta_helix; Right handed beta helix region
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