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    Abt1 activator of basal transcription 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306960, updated on 9-Dec-2024

    Summary

    Official Symbol
    Abt1provided by RGD
    Official Full Name
    activator of basal transcription 1provided by RGD
    Primary source
    RGD:1310785
    See related
    EnsemblRapid:ENSRNOG00000017585 AllianceGenome:RGD:1310785
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to act upstream of or within regulation of transcription by RNA polymerase II and spinal cord motor neuron differentiation. Predicted to be part of transcription regulator complex. Predicted to be active in nucleolus. Orthologous to human ABT1 (activator of basal transcription 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 115.0), Adrenal (RPKM 87.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Abt1 in Genome Data Viewer
    Location:
    17p11
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (42127173..42129281)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (41699151..41701253)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (43946118..43948224)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene transfer RNA tyrosine (anticodon GUA) 7 Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene uncharacterized LOC108348562 Neighboring gene transfer RNA valine (anticodon AAC) 14 Neighboring gene transfer RNA valine (anticodon CAC)

    Genomic regions, transcripts, and products

    General gene information

    General protein information

    Preferred Names
    activator of basal transcription 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025674.1NP_001020845.1  activator of basal transcription 1

      See identical proteins and their annotated locations for NP_001020845.1

      Status: VALIDATED

      Source sequence(s)
      BC099109, CV121702
      UniProtKB/Swiss-Prot
      Q4KLM5
      UniProtKB/TrEMBL
      A6KLQ7
      Related
      ENSRNOP00000023648.4, ENSRNOT00000023649.7
      Conserved Domains (1) summary
      cd12263
      Location:47151
      RRM_ABT1_like; RNA recognition motif found in activator of basal transcription 1 (ABT1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      42127173..42129281
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276442.1XP_063132512.1  activator of basal transcription 1 isoform X1

    2. XM_006253972.5XP_006254034.1  activator of basal transcription 1 isoform X2

      Conserved Domains (1) summary
      cd12263
      Location:47140
      RRM_ABT1_like; RNA recognition motif found in activator of basal transcription 1 (ABT1) and similar proteins