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    Slc33a1 solute carrier family 33 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64018, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc33a1provided by RGD
    Official Full Name
    solute carrier family 33 member 1provided by RGD
    Primary source
    RGD:620653
    See related
    EnsemblRapid:ENSRNOG00000010023 AllianceGenome:RGD:620653
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Acatn
    Summary
    Predicted to enable acetyl-CoA transmembrane transporter activity and protein homodimerization activity. Predicted to be involved in acetyl-CoA transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 42. Orthologous to human SLC33A1 (solute carrier family 33 member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 245.5), Kidney (RPKM 221.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc33a1 in Genome Data Viewer
    Location:
    2q31
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (150565327..150587700, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (148415660..148438182, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (154520170..154542981, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene phospholipase C, eta 1 Neighboring gene similar to human chromosome 3 open reading frame 33 Neighboring gene guanine monophosphate synthase Neighboring gene vomeronasal 2 receptor 44

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane  

    General protein information

    Preferred Names
    acetyl-coenzyme A transporter 1
    Names
    AT-1
    acetyl-CoA transporter 1
    acetyl-coenzyme A transporter 1-like
    solute carrier family 33 (acetyl-CoA transporter), member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022252.2NP_071588.2  acetyl-coenzyme A transporter 1

      See identical proteins and their annotated locations for NP_071588.2

      Status: PROVISIONAL

      Source sequence(s)
      BC078832
      UniProtKB/Swiss-Prot
      Q6AYY8, Q9JM68
      UniProtKB/TrEMBL
      A6JVP5
      Related
      ENSRNOP00000013392.3, ENSRNOT00000013392.7
      Conserved Domains (1) summary
      TIGR00901
      Location:86459
      2A0125; AmpG-like permease

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      150565327..150587700 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008761058.2XP_008759280.1  acetyl-coenzyme A transporter 1 isoform X1

      See identical proteins and their annotated locations for XP_008759280.1

      UniProtKB/Swiss-Prot
      Q6AYY8, Q9JM68
      UniProtKB/TrEMBL
      A6JVP5
      Conserved Domains (1) summary
      TIGR00901
      Location:86459
      2A0125; AmpG-like permease
    2. XM_039103030.2XP_038958958.1  acetyl-coenzyme A transporter 1 isoform X3

      Conserved Domains (1) summary
      cl28910
      Location:48270
      MFS; Major Facilitator Superfamily
    3. XM_063282448.1XP_063138518.1  acetyl-coenzyme A transporter 1 isoform X2

    4. XM_039103029.2XP_038958957.1  acetyl-coenzyme A transporter 1 isoform X2

      Conserved Domains (1) summary
      cl28910
      Location:14236
      MFS; Major Facilitator Superfamily
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