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    Glb1l2 galactosidase, beta 1-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 503194, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Glb1l2provided by RGD
    Official Full Name
    galactosidase, beta 1-like 2provided by RGD
    Primary source
    RGD:1564436
    See related
    EnsemblRapid:ENSRNOG00000007561 AllianceGenome:RGD:1564436
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564436
    Summary
    Predicted to enable beta-galactosidase activity. Predicted to be involved in galactose catabolic process. Predicted to be active in vacuole. Orthologous to human GLB1L2 (galactosidase beta 1 like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 117.0), Heart (RPKM 39.6) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Glb1l2 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (33391201..33442587, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (25115462..25166843, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (27805139..27853080, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094098 Neighboring gene U7 small nuclear RNA Neighboring gene beta-1,3-glucuronyltransferase 1 Neighboring gene galactosidase, beta 1-like 3 Neighboring gene pescadillo ribosomal biogenesis factor 1, pseudogene 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables beta-galactosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in galactose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in vacuole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    beta-galactosidase-1-like protein 2
    NP_001178947.1
    XP_006242800.1
    XP_017451348.1
    XP_038937926.1
    XP_038937927.1
    XP_038937928.1
    XP_038937929.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192018.1 → NP_001178947.1  beta-galactosidase-1-like protein 2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A8I6AJ82, D3ZHQ5
      Related
      ENSRNOP00000093666.1, ENSRNOT00000109550.2
      Conserved Domains (1) summary
      pfam01301
      Location:69 → 382
      Glyco_hydro_35; Glycosyl hydrolases family 35

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      33391201..33442587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081998.2 → XP_038937926.1  beta-galactosidase-1-like protein 2 isoform X1

      UniProtKB/TrEMBL
      D3ZHQ5
      Related
      ENSRNOP00000077667.2, ENSRNOT00000118429.2
      Conserved Domains (1) summary
      pfam01301
      Location:109 → 422
      Glyco_hydro_35; Glycosyl hydrolases family 35

    2. XM_039081999.2 → XP_038937927.1  beta-galactosidase-1-like protein 2 isoform X2

      UniProtKB/TrEMBL
      D3ZHQ5
      Conserved Domains (1) summary
      pfam01301
      Location:69 → 382
      Glyco_hydro_35; Glycosyl hydrolases family 35

    3. XM_039082000.2 → XP_038937928.1  beta-galactosidase-1-like protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I5Y144, D3ZHQ5
      Related
      ENSRNOP00000077046.1, ENSRNOT00000097030.2
      Conserved Domains (1) summary
      pfam01301
      Location:53 → 366
      Glyco_hydro_35; Glycosyl hydrolases family 35

    4. XM_039082001.2 → XP_038937929.1  beta-galactosidase-1-like protein 2 isoform X6

      Conserved Domains (2) summary
      COG1874
      Location:61 → 396
      GanA; Beta-galactosidase GanA [Carbohydrate transport and metabolism]
      cl38930
      Location:1 → 155
      AmyAc_family; Alpha amylase catalytic domain family

    5. XM_017595859.3 → XP_017451348.1  beta-galactosidase-1-like protein 2 isoform X4

      UniProtKB/TrEMBL
      D3ZHQ5

    6. XM_006242738.5 → XP_006242800.1  beta-galactosidase-1-like protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6ARG8, D3ZHQ5
      Related
      ENSRNOP00000105905.1, ENSRNOT00000149078.1
      Conserved Domains (1) summary
      pfam01301
      Location:53 → 366
      Glyco_hydro_35; Glycosyl hydrolases family 35
    Nucleotide Protein Strain
    Heading Accession and Version

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