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    Zfp654 zinc finger protein 654 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288354, updated on 27-Dec-2024

    Summary

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    Symbol
    Zfp654provided by RGD
    Full Name
    zinc finger protein 654provided by RGD
    Primary source
    RGD:1308321
    See related
    EnsemblRapid:ENSRNOG00000029956 AllianceGenome:RGD:1308321
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf654; RGD1308321; AABR07033023.1
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF654 (zinc finger protein 654). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 122.7), Thymus (RPKM 95.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp654 in Genome Data Viewer
    Location:
    11p12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (15947425..16011957, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (2500892..2565552, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (1831378..1895814, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ATP synthase membrane subunit g, pseudogene 6 Neighboring gene similar to human chromosome 3 open reading frame 38 Neighboring gene RNA polymerase II, I and III subunit E, pseudogene 1 Neighboring gene CGG triplet repeat binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 654

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430768.1 → NP_001417697.1  zinc finger protein 654 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      D3ZMK5

    2. NM_001430769.1 → NP_001417698.1  zinc finger protein 654 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6K4W1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      15947425..16011957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_237855.11 → XP_237855.6  zinc finger protein 654 isoform X1

      Related
      ENSRNOP00000039110.4, ENSRNOT00000050533.5
      Conserved Domains (2) summary
      sd00017
      Location:787 → 807
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:815 → 867
      zf-C2H2_8; C2H2-type zinc ribbon

    2. XM_063270836.1 → XP_063126906.1  zinc finger protein 654 isoform X2

    3. XM_039088760.2 → XP_038944688.1  zinc finger protein 654 isoform X2

      UniProtKB/TrEMBL
      A6K4W1
      Conserved Domains (2) summary
      sd00017
      Location:575 → 595
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd20908
      Location:332 → 401
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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