U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Paqr5 progestin and adipoQ receptor family member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315741, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Paqr5provided by RGD
    Official Full Name
    progestin and adipoQ receptor family member 5provided by RGD
    Primary source
    RGD:1311259
    See related
    EnsemblRapid:ENSRNOG00000014164 AllianceGenome:RGD:1311259
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pmrgamma; RGD1311259
    Summary
    Predicted to enable signaling receptor activity. Predicted to be located in membrane. Orthologous to human PAQR5 (progestin and adipoQ receptor family member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 223.9), Testes (RPKM 108.9) and 1 other tissue See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Paqr5 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (71327397..71409201, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (62431867..62513688, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (66899990..66976010, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein lateral stalk subunit P1 Neighboring gene kinesin family member 23 Neighboring gene glucuronic acid epimerase Neighboring gene sperm equatorial segment protein 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Decreased renal expression of PAQR5 is associated with the absence of a nephroprotective effect of progesterone in a rat UUO model. Abramicheva PA, et al. Sci Rep, 2023 Aug 8. PMID 37553369, Free PMC Article
    2. Expression and regulation of progestin membrane receptors in the rat corpus luteum. Cai Z, et al. Endocrinology, 2005 Dec. PMID 16123161
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Decreased renal expression of PAQR5 is associated with the absence of a nephroprotective effect of progesterone in a rat UUO model.
      Title: Decreased renal expression of PAQR5 is associated with the absence of a nephroprotective effect of progesterone in a rat UUO model.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    membrane progestin receptor gamma
    Names
    progestin and adipoQ receptor family member V
    progestin membrane receptor gamma

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014092.2 → NP_001014114.1  membrane progestin receptor gamma isoform 1

      See identical proteins and their annotated locations for NP_001014114.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J571, F7EWQ0, Q4JHE5, Q5PQT5
      Related
      ENSRNOP00000018986.4, ENSRNOT00000018988.6
      Conserved Domains (1) summary
      pfam03006
      Location:43 → 269
      HlyIII; Haemolysin-III related

    2. NM_001433773.1 → NP_001420702.1  membrane progestin receptor gamma isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J571, F7EWQ0, Q4JHE5, Q5PQT5

    3. NM_001433774.1 → NP_001420703.1  membrane progestin receptor gamma isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A8I6AFE8, A0A8I6AME0, Q4JHE5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      71327397..71409201 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006243209.5 → XP_006243271.1  membrane progestin receptor gamma isoform X1

      Related
      ENSRNOP00000095313.1, ENSRNOT00000110790.2
      Conserved Domains (1) summary
      pfam03006
      Location:29 → 255
      HlyIII; Haemolysin-III related

    2. XM_039081492.2 → XP_038937420.1  membrane progestin receptor gamma isoform X2

      Conserved Domains (1) summary
      cl03831
      Location:14 → 154
      HlyIII; Haemolysin-III related
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools