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    Rabl6 RAB, member RAS oncogene family-like 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362084, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rabl6provided by RGD
    Official Full Name
    RAB, member RAS oncogene family-like 6provided by RGD
    Primary source
    RGD:1307615
    See related
    EnsemblRapid:ENSRNOG00000016795 AllianceGenome:RGD:1307615
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307615
    Summary
    Predicted to enable GTP binding activity. Predicted to be located in centrosome and cytoplasm. Predicted to be active in cytosol and nucleus. Orthologous to human RABL6 (RAB, member RAS oncogene family like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 229.3), Muscle (RPKM 189.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rabl6 in Genome Data Viewer
    Location:
    3p13
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (28800802..28826722, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8402666..8428588, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (2806777..2832697, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene phosphohistidine phosphatase 1 Neighboring gene apical junction component 1 homolog Neighboring gene coiled-coil domain containing 183 Neighboring gene transmembrane protein 141

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding  
    enables GTP binding  
    Component Evidence Code Pubs
    located_in centrosome  
    located_in centrosome  
    located_in cytoplasm  
    is_active_in cytosol  
    located_in cytosol  
    is_active_in nucleus  
    located_in nucleus  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108573.1NP_001102043.1  rab-like protein 6

      See identical proteins and their annotated locations for NP_001102043.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474001
      UniProtKB/TrEMBL
      A6JT87, D3ZKQ4
      Related
      ENSRNOP00000060618.2, ENSRNOT00000065410.3
      Conserved Domains (2) summary
      pfam00071
      Location:45221
      Ras; Ras family
      cl21455
      Location:44221
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      28800802..28826722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105351.2XP_038961279.1  rab-like protein 6 isoform X1

      Conserved Domains (3) summary
      PRK04654
      Location:107266
      PRK04654; sec-independent translocase; Provisional
      PHA03307
      Location:177423
      PHA03307; transcriptional regulator ICP4; Provisional
      cl38936
      Location:1195
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    2. XM_039105353.2XP_038961281.1  rab-like protein 6 isoform X2

      Conserved Domains (1) summary
      PRK14951
      Location:75189
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
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