RatNP-3b defensin RatNP-3 precursor [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: RatNP-3bprovided by RGD
Full Name: defensin RatNP-3 precursorprovided by RGD
Primary source: RGD:1589653
See related: EnsemblRapid:ENSRNOG00000038135 AllianceGenome:RGD:1589653
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Np3; NP-3; NP-3a; NP-3b
Summary: Predicted to be involved in defense response to fungus and killing of cells of another organism. Orthologous to several human genes including DEFA5 (defensin alpha 5). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 280.9) See more
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Genomic context

Location:: 16q12.5

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	16	NC_086034.1 (77246811..77248977, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	16	NC_051351.1 (70544364..70546533, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	16	NC_005115.4 (75528348..75530511, complement)

Chromosome 16 - NC_086034.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

D16Wox28 (e-PCR)
- UniSTS:518806

PMC96815P3 (e-PCR)
- UniSTS:273636

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in defense response to fungus	IEA Inferred from Electronic Annotation more info
involved_in killing of cells of another organism	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: neutrophil antibiotic peptide NP-3B

Names: Neutrophil antibiotic peptide NP-3A; defensin 3a; defensin 3b; defensin NP-3; neutrophil antibiotic peptide NP-3; neutrophil defensin 3; ratNP-3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.