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    Lrrc29 leucine rich repeat containing 29 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502201, updated on 9-Dec-2024

    Summary

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    Symbol
    Lrrc29provided by RGD
    Full Name
    leucine rich repeat containing 29provided by RGD
    Primary source
    RGD:1593150
    See related
    EnsemblRapid:ENSRNOG00000025231 AllianceGenome:RGD:1593150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXL9P (F-box and leucine rich repeat protein, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 55.8), Thymus (RPKM 45.5) and 9 other tissues See more
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    Genomic context

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    See Lrrc29 in Genome Data Viewer
    Location:
    19q11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (50098274..50113488, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (33181713..33203583, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (37266782..37282076, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene engulfment and cell motility 3 Neighboring gene microRNA 6318 Neighboring gene microRNA 328 Neighboring gene transmembrane protein 208 Neighboring gene formin homology 2 domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 29

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401289.1 → NP_001388218.1  leucine-rich repeat-containing protein 29

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A8I5ZYV1, A6IYN9, F7EKW8
      Related
      ENSRNOP00000056415.3, ENSRNOT00000059663.4

    RNA

    1. NR_174679.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      50098274..50113488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097951.2 → XP_038953879.1  leucine-rich repeat-containing protein 29 isoform X6

      Conserved Domains (3) summary
      cd09293
      Location:109 → 183
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:72 → 96
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:3 → 38
      F-box-like

    2. XM_039097949.2 → XP_038953877.1  leucine-rich repeat-containing protein 29 isoform X4

      UniProtKB/TrEMBL
      B2RYK7
      Conserved Domains (3) summary
      cd09293
      Location:181 → 255
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:57 → 82
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:3 → 38
      F-box-like

    3. XM_039097950.2 → XP_038953878.1  leucine-rich repeat-containing protein 29 isoform X5

      Conserved Domains (2) summary
      cd09293
      Location:161 → 235
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:124 → 148
      LRR_AMN1; leucine-rich repeat [structural motif]

    4. XM_039097948.2 → XP_038953876.1  leucine-rich repeat-containing protein 29 isoform X3

      Conserved Domains (2) summary
      cd09293
      Location:233 → 307
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:109 → 134
      LRR_AMN1; leucine-rich repeat [structural motif]

    5. XM_006255531.5 → XP_006255593.1  leucine-rich repeat-containing protein 29 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZYV1
      Conserved Domains (3) summary
      cd09293
      Location:292 → 480
      AMN1; Antagonist of mitotic exit network protein 1
      cd00116
      Location:170 → 410
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:306 → 331
      LRR_AMN1; leucine-rich repeat [structural motif]

    6. XM_039097947.2 → XP_038953875.1  leucine-rich repeat-containing protein 29 isoform X2

      Conserved Domains (3) summary
      cd09293
      Location:292 → 391
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:173 → 206
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl39015
      Location:170 → 410
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein Strain
    Heading Accession and Version

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