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    Erg28 ergosterol biosynthesis 28 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299207, updated on 27-Dec-2024

    Summary

    Official Symbol
    Erg28provided by RGD
    Official Full Name
    ergosterol biosynthesis 28 homologprovided by RGD
    Primary source
    RGD:1310769
    See related
    EnsemblRapid:ENSRNOG00000008781 AllianceGenome:RGD:1310769
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310769
    Summary
    Predicted to enable identical protein binding activity and protein-macromolecule adaptor activity. Predicted to be involved in sterol biosynthetic process. Predicted to be located in transport vesicle. Predicted to be active in endoplasmic reticulum. Orthologous to human ERG28 (ergosterol biosynthesis 28 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 308.7), Lung (RPKM 109.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Erg28 in Genome Data Viewer
    Location:
    6q31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (111205102..111214068, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (105474112..105483078, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (109683252..109692218, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351275 Neighboring gene basic leucine zipper ATF-like transcription factor Neighboring gene uncharacterized LOC120103579 Neighboring gene FLVCR choline and putative heme transporter 2 Neighboring gene tubulin tyrosine ligase like 5 Neighboring gene uncharacterized LOC134479235 Neighboring gene transforming growth factor, beta 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in transport vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ergosterol biosynthetic protein 28 homolog
    Names
    probable ergosterol biosynthetic protein 28

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106749.1NP_001100219.1  ergosterol biosynthetic protein 28 homolog

      See identical proteins and their annotated locations for NP_001100219.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473982
      UniProtKB/TrEMBL
      A6JE40, D3ZBN4
      Related
      ENSRNOP00000012327.4, ENSRNOT00000012327.7
      Conserved Domains (1) summary
      pfam03694
      Location:8115
      Erg28; Erg28 like protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      111205102..111214068 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261754.1XP_063117824.1  ergosterol biosynthetic protein 28 homolog isoform X1