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    Nap1l1 nucleosome assembly protein 1-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 89825, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nap1l1provided by RGD
    Official Full Name
    nucleosome assembly protein 1-like 1provided by RGD
    Primary source
    RGD:71094
    See related
    EnsemblRapid:ENSRNOG00000003890 AllianceGenome:RGD:71094
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables kinase binding activity. Involved in Schwann cell proliferation and cellular response to peptide hormone stimulus. Predicted to be located in chromatin and cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human NAP1L1 (nucleosome assembly protein 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 412.4), Thymus (RPKM 367.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Nap1l1 in Genome Data Viewer
    Location:
    7q22
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (48819464..48844108)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (46933278..46957853)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (54213305..54237880)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene Bardet-Biedl syndrome 10 Neighboring gene uncharacterized LOC102548498 Neighboring gene uncharacterized LOC134479687 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene pleckstrin homology-like domain, family A, member 1 Neighboring gene uncharacterized LOC102548561

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Interactions

    General gene information

    Clone Names

    • MGC72278

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables chromatin binding  
    enables histone binding  
    enables histone chaperone activity  
    enables histone chaperone activity  
    enables kinase binding PubMed 
    Component Evidence Code Pubs
    located_in chromatin  
    located_in cytoplasm  
    located_in cytoplasm  
    located_in melanosome  
    is_active_in nucleus  
    located_in nucleus  
    located_in nucleus  
    located_in nucleus  

    General protein information

    Preferred Names
    nucleosome assembly protein 1-like 1
    Names
    NAP-1-related protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053561.2NP_446013.2  nucleosome assembly protein 1-like 1

      See identical proteins and their annotated locations for NP_446013.2

      Status: VALIDATED

      Source sequence(s)
      AF062594, BE117287, CA511505, CF110129, CO574484
      UniProtKB/Swiss-Prot
      Q9Z2G8
      UniProtKB/TrEMBL
      A6IGG5
      Related
      ENSRNOP00000086168.1, ENSRNOT00000115155.2
      Conserved Domains (1) summary
      pfam00956
      Location:76343
      NAP; Nucleosome assembly protein (NAP)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      48819464..48844108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241342.2XP_006241404.1  nucleosome assembly protein 1-like 1 isoform X1

      See identical proteins and their annotated locations for XP_006241404.1

      UniProtKB/Swiss-Prot
      Q9Z2G8
      UniProtKB/TrEMBL
      A6IGG5
      Related
      ENSRNOP00000087774.2, ENSRNOT00000109944.2
      Conserved Domains (1) summary
      pfam00956
      Location:76343
      NAP; Nucleosome assembly protein (NAP)
    2. XM_006241343.3XP_006241405.1  nucleosome assembly protein 1-like 1 isoform X2

      See identical proteins and their annotated locations for XP_006241405.1

      UniProtKB/TrEMBL
      A0A8I6AKV9, A6IGG9, A6IGH0
      Related
      ENSRNOP00000005286.7, ENSRNOT00000005286.9
      Conserved Domains (1) summary
      pfam00956
      Location:76344
      NAP; Nucleosome assembly protein (NAP)
    3. XM_006241344.5XP_006241406.1  nucleosome assembly protein 1-like 1 isoform X3

      See identical proteins and their annotated locations for XP_006241406.1

      UniProtKB/TrEMBL
      A0A8I6A4K3, A0A8I6AE93, A6IGG8
      Conserved Domains (1) summary
      pfam00956
      Location:13280
      NAP; Nucleosome assembly protein (NAP)
    4. XM_063264353.1XP_063120423.1  nucleosome assembly protein 1-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A4K3, A0A8I6AE93, A6IGG8
      Related
      ENSRNOP00000090697.1, ENSRNOT00000106121.2
    5. XM_063264354.1XP_063120424.1  nucleosome assembly protein 1-like 1 isoform X4

      UniProtKB/TrEMBL
      A6IGH0
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