U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Dmxl1 Dmx-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307429, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dmxl1provided by RGD
    Official Full Name
    Dmx-like 1provided by RGD
    Primary source
    RGD:1307692
    See related
    EnsemblRapid:ENSRNOG00000024671 AllianceGenome:RGD:1307692
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in vacuolar acidification. Predicted to be part of RAVE complex. Orthologous to human DMXL1 (Dmx like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 420.4), Thymus (RPKM 326.3) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dmxl1 in Genome Data Viewer
    Location:
    18q11
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (45179505..45349999)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (42993292..43163457)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (44468762..44644769)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098148 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene ribosomal protein L15, pseudogene 11 Neighboring gene uncharacterized LOC120098294 Neighboring gene TNF alpha induced protein 8 Neighboring gene uncharacterized LOC120098293

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in vacuolar acidification  
    Component Evidence Code Pubs
    part_of RAVE complex  

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107388.2NP_001100858.2  dmX-like protein 1

      Status: VALIDATED

      Source sequence(s)
      FQ200391, JAXUCZ010000018
      UniProtKB/TrEMBL
      A0A8I6A9G2, A6IWZ8
      Related
      ENSRNOP00000088454.1, ENSRNOT00000094956.2
      Conserved Domains (3) summary
      sd00039
      Location:27902835
      7WD40; WD40 repeat [structural motif]
      pfam12234
      Location:11411876
      Rav1p_C; RAVE protein 1 C terminal
      cl29593
      Location:27463003
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      45179505..45349999
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601109.3XP_017456598.1  dmX-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A9G2
    2. XM_006254710.5XP_006254772.1  dmX-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006254772.1

      UniProtKB/TrEMBL
      A0A8I6A9G2
      Conserved Domains (4) summary
      COG2319
      Location:28383080
      WD40; WD40 repeat [General function prediction only]
      pfam12234
      Location:11411876
      Rav1p_C; RAVE protein 1 C terminal
      sd00039
      Location:28492894
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:28053062
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. XM_006254711.5XP_006254773.1  dmX-like protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006254773.1

      UniProtKB/TrEMBL
      A0A8I5ZU67, A0A8I6A9G2
      Related
      ENSRNOP00000082026.1, ENSRNOT00000113305.2
      Conserved Domains (4) summary
      COG2319
      Location:28173059
      WD40; WD40 repeat [General function prediction only]
      pfam12234
      Location:11411876
      Rav1p_C; RAVE protein 1 C terminal
      sd00039
      Location:28282873
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:27843041
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    4. XM_006254712.5XP_006254774.1  dmX-like protein 1 isoform X3

      See identical proteins and their annotated locations for XP_006254774.1

      UniProtKB/TrEMBL
      A0A8I6A9G2, D4AA13
      Related
      ENSRNOP00000033699.4, ENSRNOT00000031812.7
      Conserved Domains (4) summary
      COG2319
      Location:28003042
      WD40; WD40 repeat [General function prediction only]
      pfam12234
      Location:11411876
      Rav1p_C; RAVE protein 1 C terminal
      sd00039
      Location:28112856
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:27673024
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    External link. Please review our privacy policy.