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    Pradc1 protease-associated domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 686393, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pradc1provided by RGD
    Official Full Name
    protease-associated domain containing 1provided by RGD
    Primary source
    RGD:1583112
    See related
    EnsemblRapid:ENSRNOG00000050483 AllianceGenome:RGD:1583112
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in extracellular region. Orthologous to human PRADC1 (protease associated domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 77.0), Kidney (RPKM 72.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Pradc1 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (119542239..119546536, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (117984732..117989710, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (117230523..117235496, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene notochord homeobox Neighboring gene SMYD family member 5 Neighboring gene chaperonin containing TCP1 subunit 7 Neighboring gene F-box protein 41

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    protease-associated domain containing 1; protease-associated domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431907.1NP_001418836.1  protease-associated domain containing 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A8I6A5A4, A6IAR8, M0R5K7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      119542239..119546536 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236797.5XP_006236859.1  protease-associated domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006236859.1

      UniProtKB/TrEMBL
      A0A8I6AQD2
      Related
      ENSRNOP00000096090.1, ENSRNOT00000101311.2
      Conserved Domains (1) summary
      cl28883
      Location:51112
      PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...
    2. XM_003749786.6XP_003749834.1  protease-associated domain-containing protein 1 isoform X1

      Related
      ENSRNOP00000064676.1, ENSRNOT00000073135.5
      Conserved Domains (1) summary
      cd02127
      Location:51168
      PA_hPAP21_like; Protease-associated domain containing proteins like the human secreted glycoprotein hPAP21 (human protease-associated domain-containing protein, 21kDa). This group contains various PA domain-containing proteins similar to hPAP21. Complex N-glycosylation ...