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    Eaf1 ELL associated factor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306261, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eaf1provided by RGD
    Official Full Name
    ELL associated factor 1provided by RGD
    Primary source
    RGD:1310057
    See related
    EnsemblRapid:ENSRNOG00000019559 AllianceGenome:RGD:1310057
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transcription elongation factor activity. Predicted to be involved in regulation of transcription elongation by RNA polymerase II and transcription elongation by RNA polymerase II. Predicted to be located in intercellular bridge and nuclear body. Predicted to be part of transcription elongation factor complex. Orthologous to human EAF1 (ELL associated factor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 77.1), Thymus (RPKM 62.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eaf1 in Genome Data Viewer
    Location:
    16p16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (6704727..6719476)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (6698322..6713071)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (7588217..7602966)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134482448 Neighboring gene SH3-domain binding protein 5 Neighboring gene uncharacterized LOC134482449 Neighboring gene methyltransferase 6, tRNA N3-cytidine Neighboring gene collagen like tail subunit of asymmetric acetylcholinesterase Neighboring gene uncharacterized LOC134482450 Neighboring gene 2-hydroxyacyl-CoA lyase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in intercellular bridge  
    located_in intercellular bridge  
    located_in intracellular membrane-bounded organelle  
    located_in nuclear body  
    located_in nuclear body  
    located_in nucleoplasm  
    part_of super elongation complex  
    part_of transcription elongation factor complex  
    part_of transcription elongation factor complex  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107293.1NP_001100763.1  ELL-associated factor 1

      See identical proteins and their annotated locations for NP_001100763.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474046
      UniProtKB/TrEMBL
      A6KFY7, D4A2G7
      Related
      ENSRNOP00000026525.5, ENSRNOT00000026525.7
      Conserved Domains (1) summary
      pfam09816
      Location:102200
      EAF; RNA polymerase II transcription elongation factor

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      6704727..6719476
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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