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    Rpl34 ribosomal protein L34 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362041, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rpl34provided by RGD
    Official Full Name
    ribosomal protein L34provided by RGD
    Primary source
    RGD:1309402
    See related
    EnsemblRapid:ENSRNOG00000016387 AllianceGenome:RGD:1309402
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rpl34l2
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL34 (ribosomal protein L34). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 1952.5), Thymus (RPKM 1898.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rpl34 in Genome Data Viewer
    Location:
    2q43
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (221958551..221962309, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (219284373..219288108, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (235850281..235854021, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485967 Neighboring gene oligosaccharyltransferase complex non-catalytic subunit Neighboring gene uncharacterized LOC134485685 Neighboring gene uncharacterized LOC108350107 Neighboring gene ribosomal protein L21 like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The primary structure of rat ribosomal protein L34. Aoyama Y, et al. FEBS Lett, 1989 May 22. PMID 2721685
    2. Isolation of eukaryotic ribosomal proteins. Purification and characterization of 60 S ribosomal subunit proteins L3, L6, L7', L8, L10, L15, L17, L18, L19, L23', L25, L27', L28, L29, L31, L32, L34, L35, L36, L36', and L37'. Tsurugi K, et al. J Biol Chem, 1977 Jun 10. PMID 863909
    3. The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. Topalidou I, et al. PLoS Genet, 2016 May. PMID 27191843, Free PMC Article
    4. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. Odintsova TI, et al. J Protein Chem, 2003 Apr. PMID 12962325
    5. Structures of the human and Drosophila 80S ribosome. Anger AM, et al. Nature, 2013 May 2. PMID 23636399

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL34
    Names
    60S ribosomal protein L34
    ribosomal protein L34-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108567.2 → NP_001102037.1  large ribosomal subunit protein eL34

      See identical proteins and their annotated locations for NP_001102037.1

      Status: PROVISIONAL

      Source sequence(s)
      BC167113
      UniProtKB/TrEMBL
      A6HVR8, A6HVR9, B2RZD4, D4A4W9
      Related
      ENSRNOP00000009046.5, ENSRNOT00000009046.10
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      221958551..221962309 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233314.5 → XP_006233376.1  large ribosomal subunit protein eL34 isoform X1

      See identical proteins and their annotated locations for XP_006233376.1

      UniProtKB/TrEMBL
      A6HVR8, A6HVR9, B2RZD4, D4A4W9
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e

    2. XM_039102721.2 → XP_038958649.1  large ribosomal subunit protein eL34 isoform X1

      UniProtKB/TrEMBL
      A6HVR8, A6HVR9, B2RZD4, D4A4W9
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11250.3 GenPept UniProtKB/Swiss-Prot:P11250

    Gene LinkOut

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