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    Vom2r44 vomeronasal 2 receptor 44 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 266778, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vom2r44provided by RGD
    Official Full Name
    vomeronasal 2 receptor 44provided by RGD
    Primary source
    RGD:708515
    See related
    EnsemblRapid:ENSRNOG00000078605 AllianceGenome:RGD:708515
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Casrl1
    Summary
    Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Located in dendrite. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 21.6), Brain (RPKM 15.0) and 9 other tissues See more
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    Genomic context

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    See Vom2r44 in Genome Data Viewer
    Location:
    2q31
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (150643126..150685691)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (148497150..148536036)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (154601995..154636154)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 33 member 1 Neighboring gene guanine monophosphate synthase Neighboring gene vomeronasal 2 receptor, 45 Neighboring gene vomeronasal 2 receptor, 46

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Co-expression of putative pheromone receptors in the sensory neurons of the vomeronasal organ. Martini S, et al. J Neurosci, 2001 Feb 1. PMID 11157070, Free PMC Article
    2. A new multigene family of putative pheromone receptors. Ryba NJ, et al. Neuron, 1997 Aug. PMID 9292726
    3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pheromone receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal type-2 receptor 1
    Names
    calcium-sensing receptor like 1
    tissue-type vomeronasal neurons putative pheromone receptor V2R2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001415021.1 → NP_001401950.1  vomeronasal type-2 receptor 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      150643126..150685691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017590655.3 → XP_017446144.1  vomeronasal type-2 receptor 1 isoform X2

      Conserved Domains (4) summary
      pfam00003
      Location:502 → 746
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:31 → 384
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:428 → 478
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:22 → 418
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    2. XM_006232438.5 → XP_006232500.1  vomeronasal type-2 receptor 1 isoform X1

      See identical proteins and their annotated locations for XP_006232500.1

      UniProtKB/TrEMBL
      A6JVP8, F1LQ12, G3V7C5
      Related
      ENSRNOP00000099000.1, ENSRNOT00000132683.1
      Conserved Domains (4) summary
      pfam00003
      Location:622 → 866
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam01094
      Location:86 → 504
      ANF_receptor; Receptor family ligand binding region
      pfam07562
      Location:548 → 598
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:46 → 538
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001099498.1: Suppressed sequence

      Description
      NM_001099498.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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