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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001270783.1 → NP_001257712.1 thyroglobulin isoform 2 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
- Source sequence(s)
-
JAXUCZ010000007
- UniProtKB/TrEMBL
- A0A0G2JXY8, G5ENA7
- Conserved Domains (5) summary
-
- smart00211
Location:1471 → 1518
- TY; Thyroglobulin type I repeats
- cd00191
Location:96 → 161
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- pfam00135
Location:2150 → 2671
- COesterase; Carboxylesterase family
- pfam07699
Location:1416 → 1461
- GCC2_GCC3; GCC2 and GCC3
- cl00150
Location:682 → 728
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
-
NM_001270784.1 → NP_001257713.1 thyroglobulin isoform 3 precursor
See identical proteins and their annotated locations for NP_001257713.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) consists of only the first five exons plus an alternate 3' exon compared to variant 1. The resulting isoform (3) has a much shorter and distinct C-terminus compared to isoform 1. This variant has been described in PMID:2325666.
- Source sequence(s)
-
JAXUCZ010000007
- UniProtKB/TrEMBL
- A0A8I6AAP3, A6HRR7
- Related
- ENSRNOP00000089860.1, ENSRNOT00000083264.4
- Conserved Domains (1) summary
-
- cd00191
Location:96 → 161
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
-
NM_030988.2 → NP_112250.2 thyroglobulin isoform 1 precursor
See identical proteins and their annotated locations for NP_112250.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
JAXUCZ010000007
- UniProtKB/Swiss-Prot
- P06882, Q9JKY6, Q9JM94
- UniProtKB/TrEMBL
- A6HRR6, G3V6V3
- Conserved Domains (5) summary
-
- smart00211
Location:1519 → 1566
- TY; Thyroglobulin type I repeats
- cd00191
Location:96 → 161
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- pfam00135
Location:2198 → 2719
- COesterase; Carboxylesterase family
- pfam07699
Location:1464 → 1509
- GCC2_GCC3; GCC2 and GCC3
- cl00150
Location:164 → 249
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCr8
Genomic
-
NC_086025.1 Reference GRCr8
- Range
-
100307349..100492246
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)