Gpr31 G protein-coupled receptor 31 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gpr31provided by RGD
Official Full Name: G protein-coupled receptor 31provided by RGD
Primary source: RGD:1305187
See related: EnsemblRapid:ENSRNOG00000072725 AllianceGenome:RGD:1305187
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable arachidonate binding activity and bioactive lipid receptor activity. Predicted to be involved in several processes, including response to acidic pH; response to ischemia; and response to molecule of bacterial origin. Predicted to be located in plasma membrane. Orthologous to human GPR31 (G protein-coupled receptor 31). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 1q12

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (55474484..55475443, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (52926953..52927912, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (53519829..53520788, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	ISO Inferred from Sequence Orthology more info
enables arachidonate binding	ISO Inferred from Sequence Orthology more info
enables bioactive lipid receptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of inflammatory response	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of immune response	ISO Inferred from Sequence Orthology more info
involved_in response to acidic pH	ISO Inferred from Sequence Orthology more info
involved_in response to ischemia	ISO Inferred from Sequence Orthology more info
involved_in response to molecule of bacterial origin	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001169132.1 → NP_001162603.1 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

D3ZIT6

Related

ENSRNOP00000100262.1, ENSRNOT00000152006.1

Conserved Domains (1) summary

pfam00001
Location:31 → 282

7tm_1; 7 transmembrane receptor (rhodopsin family)