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    Taf9b TATA-box binding protein associated factor 9b [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171152, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Taf9bprovided by RGD
    Official Full Name
    TATA-box binding protein associated factor 9bprovided by RGD
    Primary source
    RGD:621116
    See related
    EnsemblRapid:ENSRNOG00000061102 AllianceGenome:RGD:621116
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dn7; Taf9l; TAFII31
    Summary
    Predicted to enable protein heterodimerization activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in programmed cell death and response to organic cyclic compound. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex and transcription factor TFTC complex. Orthologous to human TAF9B (TATA-box binding protein associated factor 9b). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 126.6), Thymus (RPKM 87.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Taf9b in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (75354823..75366166, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (71289290..71300142, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (77281234..77295238, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L19, pseudogene 17 Neighboring gene phosphoglycerate kinase 1 Neighboring gene 40S ribosomal protein S21-like Neighboring gene fibronectin type III domain containing protein 3C1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole. Stierum R, et al. Food Chem Toxicol, 2008 Aug. PMID 18539377
    2. Rat TAFII31 gene is induced upon programmed cell death in differentiated PC12 cells deprived of NGF. Aoki T, et al. Biochem Biophys Res Commun, 1997 May 8. PMID 9168994
    3. In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L. Chen Z, et al. J Biol Chem, 2003 Sep 12. PMID 12837753
    4. TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9. Frontini M, et al. Mol Cell Biol, 2005 Jun. PMID 15899866, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in programmed cell death IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to organic cyclic compound IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of transcription factor TFTC complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    transcription initiation factor TFIID subunit 9B
    Names
    DN-7
    TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31 kD
    TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
    TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor
    neuronal cell death-related gene in neuron 7
    transcription-associated factor TAFII31L
    NP_598299.2
    XP_006257055.3
    XP_006257056.3
    XP_038955366.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133615.2 → NP_598299.2  transcription initiation factor TFIID subunit 9B

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/Swiss-Prot
      Q5EAN8, Q62880
      UniProtKB/TrEMBL
      A6IV45
      Conserved Domains (1) summary
      pfam02291
      Location:5 → 125
      TFIID-31kDa; Transcription initiation factor IID, 31kD subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      75354823..75366166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006256994.5 → XP_006257056.3  transcription initiation factor TFIID subunit 9B isoform X1

      UniProtKB/TrEMBL
      A0A0G2K6Z1
      Related
      ENSRNOP00000073996.2, ENSRNOT00000090833.3

    2. XM_006256993.5 → XP_006257055.3  transcription initiation factor TFIID subunit 9B isoform X3

    3. XM_039099438.2 → XP_038955366.2  transcription initiation factor TFIID subunit 9B isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q62880.2 GenPept UniProtKB/Swiss-Prot:Q62880

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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