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    Ceacam3 CEA cell adhesion molecule 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24926, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ceacam3provided by RGD
    Official Full Name
    CEA cell adhesion molecule 3provided by RGD
    Primary source
    RGD:2333
    See related
    EnsemblRapid:ENSRNOG00000027607 AllianceGenome:RGD:2333
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cea; Cear; Cgm1; Cgm4; CGM4AA; Ceacam5; RATCEAA; RATCGM4AA
    Summary
    Predicted to be involved in T cell activation and immune response. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM21 (CEA cell adhesion molecule 21) and CEACAM7 (CEA cell adhesion molecule 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Ceacam3 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (86991944..87004518)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (77863907..77876441)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (79122593..79135127)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene carcinoembryonic antigen gene family 4 Neighboring gene pregnancy specific glycoprotein 16 Neighboring gene pregnancy-specific beta 1-glycoprotein Neighboring gene pregnancy-specific beta-1-glycoprotein 29

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal expression of pregnancy-specific glycoprotein gene rnCGM1 in rat placenta. Rebstock S, et al. Dev Dyn, 1993 Nov. PMID 8136522
    2. cDNA and gene analyses imply a novel structure for a rat carcinoembryonic antigen-related protein. Rebstock S, et al. J Biol Chem, 1990 May 15. PMID 2335509
    3. Identification of a carcinoembryonic antigen gene family in the rat. Analysis of the N-terminal domains reveals immunoglobulin-like, hypervariable regions. Kodelja V, et al. J Biol Chem, 1989 Apr 25. PMID 2708349
    4. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, et al. Genome Res, 2004 Apr. PMID 15060019, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114355

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in T cell activation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cell adhesion molecule CEACAM3; carcinoembryonic antigen-related cell adhesion molecule 3
    Names
    Carcinoembryonic antigen gene family (CGM1)
    Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein)
    carcinoembryonic antigen CGM1
    carcinoembryonic antigen gene family 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012702.2 → NP_036834.2  cell adhesion molecule CEACAM3 precursor

      See identical proteins and their annotated locations for NP_036834.2

      Status: PROVISIONAL

      Source sequence(s)
      BC098921
      UniProtKB/Swiss-Prot
      Q63101, Q63111
      UniProtKB/TrEMBL
      A6J8G0, F7FFP7, Q4KLZ7
      Related
      ENSRNOP00000023663.1, ENSRNOT00000023663.4
      Conserved Domains (3) summary
      cd05774
      Location:276 → 380
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00410
      Location:45 → 137
      IG_like; Immunoglobulin like
      cl11960
      Location:616 → 706
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      86991944..87004518
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039101138.2 → XP_038957066.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JW44
      Conserved Domains (2) summary
      cd05740
      Location:384 → 471
      IgI_hCEACAM_2_4_6_like; Immunoglobulin (Ig)-like domain of human carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) domains 2, 4, and 6, and similar domains
      cd05774
      Location:156 → 260
      IgV_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

    2. XM_063281070.1 → XP_063137140.1  carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2

      UniProtKB/TrEMBL
      A0A0G2JW44
      Related
      ENSRNOP00000069736.2, ENSRNOT00000088393.3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q63111.1 GenPept UniProtKB/Swiss-Prot:Q63111

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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