S100a7l2 S100 calcium binding protein A7 like 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: S100a7l2provided by RGD
Official Full Name: S100 calcium binding protein A7 like 2provided by RGD
Primary source: RGD:1562234
See related: EnsemblRapid:ENSRNOG00000079296 AllianceGenome:RGD:1562234
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562234
Summary: Predicted to enable S100 protein binding activity; calcium ion binding activity; and calcium-dependent protein binding activity. Predicted to be located in extracellular space. Predicted to be active in nucleus and perinuclear region of cytoplasm. Orthologous to human S100A7L2 (S100 calcium binding protein A7 like 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 482.3) See more
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Genomic context

Location:: 2q34

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (178852096..178854992)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (176506300..176509196)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (191291478..191294828, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AU026935 (e-PCR)
- UniSTS:113791

BI281560 (e-PCR)
- UniSTS:249504

BI278666 (e-PCR)
- UniSTS:244441

BI278703 (e-PCR)
- UniSTS:244448

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables S100 protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium-dependent protein binding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
is_active_in sarcoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC499657

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109187.1 → NP_001102657.1 uncharacterized protein LOC499657

See identical proteins and their annotated locations for NP_001102657.1

Status: PREDICTED

Source sequence(s)

CH474068

UniProtKB/TrEMBL

A6KMS2, D3Z9U8, D3ZTD2

Related

ENSRNOP00000058821.1, ENSRNOT00000067469.3

Conserved Domains (1) summary

cl08302
Location:17 → 84

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...