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    Tmem245 transmembrane protein 245 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298020, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmem245provided by RGD
    Official Full Name
    transmembrane protein 245provided by RGD
    Primary source
    RGD:1308958
    See related
    EnsemblRapid:ENSRNOG00000026271 AllianceGenome:RGD:1308958
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308958
    Summary
    Predicted to be located in membrane. Orthologous to human TMEM245 (transmembrane protein 245). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 219.3), Adrenal (RPKM 168.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem245 in Genome Data Viewer
    Location:
    5q24
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (76366157..76443108, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (71570952..71647915, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (73909032..73986602, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene elongator acetyltransferase complex subunit 1 Neighboring gene actin binding transcription modulator Neighboring gene catenin alpha-like 1 Neighboring gene microRNA 32 Neighboring gene ferric-chelate reductase 1-like Neighboring gene erythrocyte membrane protein band 4.1 like 4B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419571.2NP_001406500.1  transmembrane protein 245

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/Swiss-Prot
      D3ZXD8
      UniProtKB/TrEMBL
      D3ZR79
      Related
      ENSRNOP00000035996.4, ENSRNOT00000032299.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      76366157..76443108 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008763737.3XP_008761959.1  transmembrane protein 245 isoform X4

      See identical proteins and their annotated locations for XP_008761959.1

      UniProtKB/TrEMBL
      D3ZR79
      Related
      ENSRNOP00000079058.2, ENSRNOT00000103281.2
      Conserved Domains (1) summary
      cl00465
      Location:616806
      UPF0118; Domain of unknown function DUF20
    2. XM_039111408.2XP_038967336.1  transmembrane protein 245 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZM20, D3ZR79
      Related
      ENSRNOP00000103723.1, ENSRNOT00000151825.1
      Conserved Domains (1) summary
      cl00465
      Location:583829
      AI-2E_transport; AI-2E family transporter
    3. XM_216388.10XP_216388.4  transmembrane protein 245 isoform X2

      See identical proteins and their annotated locations for XP_216388.4

      UniProtKB/TrEMBL
      A0A8I6AGG4, D3ZR79
      Related
      ENSRNOP00000093041.1, ENSRNOT00000116562.2
      Conserved Domains (1) summary
      cl00465
      Location:651841
      UPF0118; Domain of unknown function DUF20
    4. XM_006238188.4XP_006238250.1  transmembrane protein 245 isoform X1

      See identical proteins and their annotated locations for XP_006238250.1

      UniProtKB/TrEMBL
      D3ZR79
      Related
      ENSRNOP00000063739.3, ENSRNOT00000064043.6
      Conserved Domains (1) summary
      cl00465
      Location:659849
      UPF0118; Domain of unknown function DUF20
    5. XM_039111410.2XP_038967338.1  transmembrane protein 245 isoform X6

      Conserved Domains (1) summary
      cl00465
      Location:214404
      AI-2E_transport; AI-2E family transporter
    6. XM_063287307.1XP_063143377.1  transmembrane protein 245 isoform X5

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