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    Samd4b sterile alpha motif domain containing 4B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308473, updated on 9-Dec-2024

    Summary

    Official Symbol
    Samd4bprovided by RGD
    Official Full Name
    sterile alpha motif domain containing 4Bprovided by RGD
    Primary source
    RGD:1305597
    See related
    EnsemblRapid:ENSRNOG00000079475 AllianceGenome:RGD:1305597
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305597
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Predicted to be located in cytosol. Predicted to be active in P-body. Orthologous to human SAMD4B (sterile alpha motif domain containing 4B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 154.4), Lung (RPKM 82.3) and 9 other tissues See more
    Orthologs
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    Try the new Transcript table

    Genomic context

    See Samd4b in Genome Data Viewer
    Location:
    1q21
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (92816955..92855243, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (83689413..83728652, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (85324017..85362266)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 29 Neighboring gene PAF1 homolog, Paf1/RNA polymerase II complex component Neighboring gene glia maturation factor, gamma Neighboring gene leucine rich repeat and fibronectin type III domain containing 1

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation repressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cerebellar neuron development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107498.1NP_001100968.1  protein Smaug homolog 2

      See identical proteins and their annotated locations for NP_001100968.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473979
      UniProtKB/TrEMBL
      A6J9J0, D4A769
      Related
      ENSRNOP00000026839.4, ENSRNOT00000026839.6
      Conserved Domains (1) summary
      cd09557
      Location:296358
      SAM_Smaug; SAM domain of Smaug subfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      92816955..92855243 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261540.1XP_063117610.1  protein Smaug homolog 2 isoform X2

    2. XM_008759143.4XP_008757365.1  protein Smaug homolog 2 isoform X1

      See identical proteins and their annotated locations for XP_008757365.1

      UniProtKB/TrEMBL
      A6J9J0, D4A769
      Related
      ENSRNOP00000076302.2, ENSRNOT00000093693.3
      Conserved Domains (1) summary
      cd09557
      Location:296358
      SAM_Smaug; SAM domain of Smaug subfamily
    3. XM_063261538.1XP_063117608.1  protein Smaug homolog 2 isoform X1

      UniProtKB/TrEMBL
      A6J9J0, D4A769