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    Zfpl1 zinc finger protein-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 684755, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfpl1provided by RGD
    Official Full Name
    zinc finger protein-like 1provided by RGD
    Primary source
    RGD:1586738
    See related
    EnsemblRapid:ENSRNOG00000050180 AllianceGenome:RGD:1586738
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human ZFPL1 (zinc finger protein like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 73.4), Lung (RPKM 70.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfpl1 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212803790..212807803, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (203374500..203378518, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (221444588..221448555, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene VPS51 subunit of GARP complex Neighboring gene microRNA 6315 Neighboring gene transmembrane protein 262 Neighboring gene cell division cycle associated 5 Neighboring gene N-acetylated alpha-linked acidic dipeptidase-like 1 Neighboring gene SAC3 domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. ZFPL1, a novel ring finger protein required for cis-Golgi integrity and efficient ER-to-Golgi transport. Chiu CF, et al. EMBO J, 2008 Apr 9. PMID 18323775, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286936.1 → NP_001273865.1  zinc finger protein-like 1

      See identical proteins and their annotated locations for NP_001273865.1

      Status: VALIDATED

      Source sequence(s)
      BU758664, CB717504, DY546174
      UniProtKB/TrEMBL
      A6HZD4, M0RCA3
      Conserved Domains (1) summary
      cd16487
      Location:50 → 104
      mRING-H2-C3DHC3_ZFPL1; Modified RING finger, H2 subclass (C3DHC3-type), found in zinc finger protein-like 1 (ZFPL1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      212803790..212807803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006230901.5 → XP_006230963.1  zinc finger protein-like 1 isoform X1

      See identical proteins and their annotated locations for XP_006230963.1

      UniProtKB/TrEMBL
      A6HZD4, M0RCA3
      Conserved Domains (1) summary
      cd16487
      Location:50 → 104
      mRING-H2-C3DHC3_ZFPL1; Modified RING finger, H2 subclass (C3DHC3-type), found in zinc finger protein-like 1 (ZFPL1) and similar proteins

    2. XM_008760175.3 → XP_008758397.1  zinc finger protein-like 1 isoform X1

      See identical proteins and their annotated locations for XP_008758397.1

      UniProtKB/TrEMBL
      A6HZD4, M0RCA3
      Related
      ENSRNOP00000067214.1, ENSRNOT00000075165.4
      Conserved Domains (1) summary
      cd16487
      Location:50 → 104
      mRING-H2-C3DHC3_ZFPL1; Modified RING finger, H2 subclass (C3DHC3-type), found in zinc finger protein-like 1 (ZFPL1) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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