U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cox19 cytochrome c oxidase assembly factor COX19 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304330, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cox19provided by RGD
    Official Full Name
    cytochrome c oxidase assembly factor COX19provided by RGD
    Primary source
    RGD:1305631
    See related
    EnsemblRapid:ENSRNOG00000050052 AllianceGenome:RGD:1305631
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305631
    Summary
    Predicted to be involved in intracellular copper ion homeostasis and mitochondrial cytochrome c oxidase assembly. Predicted to be located in cytosol and mitochondrion. Predicted to be active in mitochondrial intermembrane space. Orthologous to human COX19 (cytochrome c oxidase assembly factor COX19). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 88.6), Heart (RPKM 64.1) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cox19 in Genome Data Viewer
    Location:
    12q11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (20417389..20426868)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (15303535..15313014)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (17395624..17405103)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 7 open reading frame 50 Neighboring gene microRNA 339 Neighboring gene cytochrome P450, family 2, subfamily w, polypeptide 1 Neighboring gene ArfGAP with dual PH domains 1 Neighboring gene guided entry of tail-anchored proteins factor 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in intracellular copper ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    COX19 cytochrome c oxidase assembly homolog
    Names
    COX19 cytochrome c oxidase assembly factor
    cytochrome c oxidase assembly homolog 19
    cytochrome c oxidase assembly protein 19

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107126.2NP_001100596.1  COX19 cytochrome c oxidase assembly homolog

      See identical proteins and their annotated locations for NP_001100596.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6K1W3
      Related
      ENSRNOP00000089709.2, ENSRNOT00000118930.2
      Conserved Domains (1) summary
      pfam06747
      Location:3064
      CHCH; CHCH domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      20417389..20426868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)