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    Tmed8 transmembrane p24 trafficking protein family member 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681943, updated on 9-Dec-2024

    Summary

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    Symbol
    Tmed8provided by RGD
    Full Name
    transmembrane p24 trafficking protein family member 8provided by RGD
    Primary source
    RGD:1589336
    See related
    EnsemblRapid:ENSRNOG00000077115 AllianceGenome:RGD:1589336
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human TMED8 (transmembrane p24 trafficking protein family member 8). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 87.0), Spleen (RPKM 66.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmed8 in Genome Data Viewer
    Location:
    6q31
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (112537921..112572199, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (106806973..106841271, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (111188938..111222866, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene protein-O-mannosyltransferase 2 Neighboring gene uncharacterized LOC134479237 Neighboring gene glutathione S-transferase zeta 1 Neighboring gene sterile alpha motif domain containing 15 Neighboring gene NADP-dependent oxidoreductase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    protein TMED8; transmembrane p24 trafficking protein family member 8
    Names
    transmembrane emp24 protein transport domain containing 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432135.1 → NP_001419064.1  transmembrane p24 trafficking protein family member 8

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I5ZNC2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      112537921..112572199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039113336.2 → XP_038969264.1  protein TMED8 isoform X1

      Related
      ENSRNOP00000111888.1, ENSRNOT00000134324.1
      Conserved Domains (1) summary
      pfam13897
      Location:186 → 325
      GOLD_2; Golgi-dynamics membrane-trafficking

    2. XM_039113337.2 → XP_038969265.1  protein TMED8 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZPG0, A6JE87
      Related
      ENSRNOP00000106950.1, ENSRNOT00000165449.1
      Conserved Domains (1) summary
      pfam13897
      Location:164 → 303
      GOLD_2; Golgi-dynamics membrane-trafficking

    3. XM_063262691.1 → XP_063118761.1  protein TMED8 isoform X3

      UniProtKB/TrEMBL
      A6JE87
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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