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    Ap1g2 adaptor related protein complex 1 subunit gamma 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100362547, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ap1g2provided by RGD
    Official Full Name
    adaptor related protein complex 1 subunit gamma 2provided by RGD
    Primary source
    RGD:2324507
    See related
    EnsemblRapid:ENSRNOG00000025589 AllianceGenome:RGD:2324507
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable clathrin adaptor activity. Predicted to be involved in Golgi to vacuole transport. Predicted to be located in Golgi-associated vesicle; membrane; and transport vesicle. Predicted to be part of AP-1 adaptor complex. Predicted to be active in synapse. Orthologous to human AP1G2 (adaptor related protein complex 1 subunit gamma 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 80.1), Thymus (RPKM 79.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ap1g2 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (32541528..32549392, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (28571571..28579421, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33759108..33767017, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene neuroguidin Neighboring gene uncharacterized LOC134482119 Neighboring gene zinc finger homeobox 2 Neighboring gene thiamine triphosphatase Neighboring gene junctophilin 4 Neighboring gene dehydrogenase/reductase member 2 like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cloning, expression, and localization of a novel gamma-adaptin-like molecule. Lewin DA, et al. FEBS Lett, 1998 Sep 18. PMID 9762922
    2. Identification and characterization of novel clathrin adaptor-related proteins. Takatsu H, et al. J Biol Chem, 1998 Sep 18. PMID 9733768
    3. Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin. Page LJ, et al. J Cell Biol, 1999 Sep 6. PMID 10477754, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables clathrin adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of AP-1 adaptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi-associated vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    AP-1 complex subunit gamma-like 2
    Names
    adaptor protein complex AP-1, gamma 2 subunit
    adaptor-related protein complex 1, gamma 2 subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427245.1 → NP_001414174.1  AP-1 complex subunit gamma-like 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A6KGZ0, D3ZGW2
      Related
      ENSRNOP00000099475.1, ENSRNOT00000033722.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      32541528..32549392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063273889.1 → XP_063129959.1  AP-1 complex subunit gamma-like 2 isoform X1

      UniProtKB/TrEMBL
      A6KGY9

    2. XM_039093834.2 → XP_038949762.1  AP-1 complex subunit gamma-like 2 isoform X2

      Conserved Domains (1) summary
      pfam01602
      Location:23 → 469
      Adaptin_N; Adaptin N terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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