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    Fbxo30 F-box protein 30 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308283, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fbxo30provided by RGD
    Official Full Name
    F-box protein 30provided by RGD
    Primary source
    RGD:1359367
    See related
    EnsemblRapid:ENSRNOG00000014852 AllianceGenome:RGD:1359367
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Orthologous to human FBXO30 (F-box protein 30). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 214.3), Heart (RPKM 133.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Fbxo30 in Genome Data Viewer
    Location:
    1p13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (7475636..7491719)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (5655341..5671558)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (5366119..5389774)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SNF2 histone linker PHD RING helicase Neighboring gene uncharacterized LOC102547024 Neighboring gene small nucleolar RNA, H/ACA box 70J Neighboring gene calponin-2-like Neighboring gene EPM2A glucan phosphatase, laforin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Ebstein F, et al. Int J Biochem Cell Biol, 2009 May. PMID 19028597
    2. RNF207 exacerbates pathological cardiac hypertrophy via post-translational modification of TAB1. Yuan L, et al. Cardiovasc Res, 2023 Mar 17. PMID 35352799
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94907

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 30

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007690.1 → NP_001007691.1  F-box only protein 30

      See identical proteins and their annotated locations for NP_001007691.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083823
      UniProtKB/Swiss-Prot
      Q5XI67
      UniProtKB/TrEMBL
      A6JP44
      Related
      ENSRNOP00000112091.1, ENSRNOT00000140474.1
      Conserved Domains (2) summary
      pfam15965
      Location:8 → 100
      zf-TRAF_2; TRAF-like zinc-finger
      pfam15966
      Location:610 → 718
      F-box_4; F-box

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      7475636..7491719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006227640.5 → XP_006227702.1  F-box only protein 30 isoform X1

      See identical proteins and their annotated locations for XP_006227702.1

      UniProtKB/Swiss-Prot
      Q5XI67
      UniProtKB/TrEMBL
      A6JP44
      Related
      ENSRNOP00000019918.3, ENSRNOT00000019918.7
      Conserved Domains (2) summary
      pfam15965
      Location:8 → 100
      zf-TRAF_2; TRAF-like zinc-finger
      pfam15966
      Location:610 → 718
      F-box_4; F-box
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XI67.1 GenPept UniProtKB/Swiss-Prot:Q5XI67

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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