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    Cnih4 cornichon family member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289324, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cnih4provided by RGD
    Official Full Name
    cornichon family member 4provided by RGD
    Primary source
    RGD:1559740
    See related
    EnsemblRapid:ENSRNOG00000003717 AllianceGenome:RGD:1559740
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1559740
    Summary
    Predicted to enable CCR5 chemokine receptor binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in endoplasmic reticulum and endoplasmic reticulum-Golgi intermediate compartment. Predicted to be active in COPII-coated ER to Golgi transport vesicle and endoplasmic reticulum membrane. Orthologous to human CNIH4 (cornichon family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 100.1), Adrenal (RPKM 91.8) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cnih4 in Genome Data Viewer
    Location:
    13q26
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (95442054..95458163)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (92910315..92926428)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (99469382..99490693)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene delta(4)-desaturase, sphingolipid 1 like 2 Neighboring gene U6 spliceosomal RNA Neighboring gene nuclear VCP-like Neighboring gene WD repeat domain 26 Neighboring gene glutamic acid-rich protein-like Neighboring gene cornichon family AMPA receptor auxiliary protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables CCR5 chemokine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein cornichon homolog 4
    Names
    cornichon family AMPA receptor auxiliary protein 4
    cornichon homolog 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105981.1NP_001099451.1  protein cornichon homolog 4

      See identical proteins and their annotated locations for NP_001099451.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473985
      UniProtKB/TrEMBL
      A6JGJ5, D3ZTY0
      Related
      ENSRNOP00000004939.5, ENSRNOT00000004939.7
      Conserved Domains (1) summary
      pfam03311
      Location:3130
      Cornichon; Cornichon protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      95442054..95458163
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)