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    Ap3s2 adaptor related protein complex 3 subunit sigma 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 683402, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ap3s2provided by RGD
    Official Full Name
    adaptor related protein complex 3 subunit sigma 2provided by RGD
    Primary source
    RGD:1586888
    See related
    EnsemblRapid:ENSRNOG00000043141 AllianceGenome:RGD:1586888
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Is active in synaptic vesicle. Orthologous to human AP3S2 (adaptor related protein complex 3 subunit sigma 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 267.6), Heart (RPKM 163.1) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ap3s2 in Genome Data Viewer
    Location:
    1q31
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (143228131..143268573, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (133818825..133859269, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (141612961..141655417, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene mesoderm posterior bHLH transcription factor 2 Neighboring gene alanyl aminopeptidase, membrane Neighboring gene uncharacterized LOC134483742 Neighboring gene uncharacterized LOC120099870 Neighboring gene actin-related protein 2/3 complex inhibitor

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in anterograde axonal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in anterograde synaptic vesicle transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of AP-3 adaptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in axon cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic vesicle EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synaptic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-3 complex subunit sigma-2
    Names
    adaptor-related protein complex 3, sigma 2 subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001115039.1NP_001108511.1  AP-3 complex subunit sigma-2

      See identical proteins and their annotated locations for NP_001108511.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158881
      UniProtKB/TrEMBL
      B0BNM6, F1LVM4
      Related
      ENSRNOP00000088313.1, ENSRNOT00000096941.2
      Conserved Domains (1) summary
      cd14834
      Location:1146
      AP3_sigma; AP-3 complex subunit sigma

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      143228131..143268573 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)