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    Elfn2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100910536, updated on 9-Dec-2024

    Summary

    Official Symbol
    Elfn2provided by RGD
    Official Full Name
    extracellular leucine-rich repeat and fibronectin type III domain containing 2provided by RGD
    Primary source
    RGD:1559693
    See related
    EnsemblRapid:ENSRNOG00000007934 AllianceGenome:RGD:1559693
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Elfn2-ps1; RGD1559693
    Summary
    Predicted to be involved in synaptic membrane adhesion. Predicted to be active in extracellular matrix; extracellular space; and postsynaptic density membrane. Orthologous to human ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Elfn2 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (112101998..112153280, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (110220293..110272770, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (119889786..119897038, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene cytohesin 4 Neighboring gene uncharacterized LOC134479754 Neighboring gene uncharacterized LOC102549375 Neighboring gene MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase Neighboring gene caspase recruitment domain family, member 10

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in extracellular matrix  
    is_active_in extracellular space  
    is_active_in postsynaptic density membrane  
    is_active_in synapse  

    General protein information

    Preferred Names
    extracellular leucine-rich repeat and fibronectin type III domain containing 2; protein phosphatase 1 regulatory subunit 29
    Names
    extracellular leucine-rich repeat and fibronectin type III containing 2
    extracellular leucine-rich repeat and fibronectin type III domain containing 2, pseudogene 1
    protein phosphatase 1 regulatory subunit 29-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432228.1 → NP_001419157.1  extracellular leucine-rich repeat and fibronectin type III domain containing 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6HSL8, D3ZH36

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      112101998..112153280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006242041.5 → XP_006242103.2  protein phosphatase 1 regulatory subunit 29

      UniProtKB/TrEMBL
      A6HSL8, D3ZH36
      Related
      ENSRNOP00000112651.1, ENSRNOT00000167735.1
      Conserved Domains (4) summary
      TIGR00864
      Location:157 → 227
      PCC; polycystin cation channel protein
      sd00031
      Location:60 → 80
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:200 → 226
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:80 → 139
      LRR_8; Leucine rich repeat
    2. XM_039080278.2 → XP_038936206.1  protein phosphatase 1 regulatory subunit 29

      Related
      ENSRNOP00000010609.3, ENSRNOT00000010609.6
      Conserved Domains (4) summary
      TIGR00864
      Location:157 → 227
      PCC; polycystin cation channel protein
      sd00031
      Location:60 → 80
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:200 → 226
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:80 → 139
      LRR_8; Leucine rich repeat
    3. XM_039080277.2 → XP_038936205.1  protein phosphatase 1 regulatory subunit 29

      UniProtKB/TrEMBL
      A6HSL8, D3ZH36
      Related
      ENSRNOP00000096572.1, ENSRNOT00000105973.2
      Conserved Domains (4) summary
      TIGR00864
      Location:157 → 227
      PCC; polycystin cation channel protein
      sd00031
      Location:60 → 80
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:200 → 226
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:80 → 139
      LRR_8; Leucine rich repeat
    4. XM_039080276.2 → XP_038936204.1  protein phosphatase 1 regulatory subunit 29

      UniProtKB/TrEMBL
      A6HSL8, D3ZH36
      Conserved Domains (4) summary
      TIGR00864
      Location:157 → 227
      PCC; polycystin cation channel protein
      sd00031
      Location:60 → 80
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:200 → 226
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:80 → 139
      LRR_8; Leucine rich repeat
    5. XM_063264450.1 → XP_063120520.1  protein phosphatase 1 regulatory subunit 29

      UniProtKB/TrEMBL
      A6HSL8, D3ZH36
      Related
      ENSRNOP00000103739.1, ENSRNOT00000146524.1
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