U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    Itpk1 inositol-tetrakisphosphate 1-kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500709, updated on 9-Dec-2024

    Summary

    Official Symbol
    Itpk1provided by RGD
    Official Full Name
    inositol-tetrakisphosphate 1-kinaseprovided by RGD
    Primary source
    RGD:1595691
    See related
    EnsemblRapid:ENSRNOG00000008051 AllianceGenome:RGD:1595691
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable inositol phosphate kinase activity. Predicted to be involved in necroptotic process. Predicted to act upstream of or within neural tube development. Predicted to be located in apical plasma membrane. Orthologous to human ITPK1 (inositol-tetrakisphosphate 1-kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 48.7), Thymus (RPKM 39.2) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Itpk1 in Genome Data Viewer
    Location:
    6q32
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (127475589..127609320, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (121710750..121844501, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (126448920..126582188, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103692694 Neighboring gene chromogranin A Neighboring gene uncharacterized LOC102548189 Neighboring gene uncharacterized LOC102548370 Neighboring gene modulator of apoptosis 1 Neighboring gene GON7 subunit of KEOPS complex

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in apical plasma membrane  

    General protein information

    Preferred Names
    inositol-tetrakisphosphate 1-kinase
    Names
    inositol 1,3,4-triphosphate 5/6 kinase
    NP_001178914.1
    XP_008763064.1
    XP_017449793.1
    XP_038968683.1
    XP_063118403.1
    XP_063118404.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191985.1NP_001178914.1  inositol-tetrakisphosphate 1-kinase

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6AUY6, D3ZQM7
      Related
      ENSRNOP00000010656.7, ENSRNOT00000010656.9
      Conserved Domains (1) summary
      cl17255
      Location:1318
      ATP-grasp_4; ATP-grasp domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      127475589..127609320 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112755.2XP_038968683.1  inositol-tetrakisphosphate 1-kinase isoform X4

      Conserved Domains (1) summary
      cl17255
      Location:1241
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
    2. XM_017594304.3XP_017449793.1  inositol-tetrakisphosphate 1-kinase isoform X1

      UniProtKB/TrEMBL
      A0A0G2K7L4, A0A8I6AUY6
      Related
      ENSRNOP00000074255.1, ENSRNOT00000080829.3
    3. XM_063262334.1XP_063118404.1  inositol-tetrakisphosphate 1-kinase isoform X4

    4. XM_008764842.4XP_008763064.1  inositol-tetrakisphosphate 1-kinase isoform X2

      UniProtKB/TrEMBL
      A0A8I6AUY6
      Conserved Domains (1) summary
      cl17255
      Location:7327
      ATP-grasp_4; ATP-grasp domain
    5. XM_063262333.1XP_063118403.1  inositol-tetrakisphosphate 1-kinase isoform X3

      UniProtKB/TrEMBL
      A0A8I6AUQ3, A0A8I6AUY6
      Related
      ENSRNOP00000097242.1, ENSRNOT00000095173.2
    External link. Please review our privacy policy.