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    Zfp120 zinc finger protein 120 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102554315, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp120provided by RGD
    Official Full Name
    zinc finger protein 120provided by RGD
    Primary source
    RGD:7747897
    See related
    EnsemblRapid:ENSRNOG00000067071 AllianceGenome:RGD:7747897
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF490 (zinc finger protein 490). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 79.9), Thymus (RPKM 69.5) and 9 other tissues See more
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    Genomic context

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    See Zfp120 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (159206172..159251493)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (138763244..138791042)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (145636480..145663908, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 442 Neighboring gene uncharacterized LOC134486179 Neighboring gene UPF0472 protein C16orf72 homolog pseudogene Neighboring gene ArfGAP with FG repeats 1, pseudogene 1 Neighboring gene RIKEN cDNA 3300002I08 gene like 1 Neighboring gene uncharacterized LOC102554820 Neighboring gene sperm motility kinase x like 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 120
    Names
    zinc finger protein 596-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431867.1 → NP_001418796.1  zinc finger protein 120 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I5Y958

    2. NM_001431868.1 → NP_001418797.1  zinc finger protein 120 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    3. NM_001431869.1 → NP_001418798.1  zinc finger protein 120 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      159206172..159251493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285044.1 → XP_063141114.1  zinc finger protein 120 isoform X4

    2. XM_063285043.1 → XP_063141113.1  zinc finger protein 120 isoform X2

      Related
      ENSRNOP00000103282.1, ENSRNOT00000158597.1

    3. XM_006235189.5 → XP_006235251.1  zinc finger protein 120 isoform X1

      Related
      ENSRNOP00000076862.1, ENSRNOT00000104232.2
      Conserved Domains (5) summary
      smart00349
      Location:28 → 69
      KRAB; krueppel associated box
      COG5048
      Location:51 → 362
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:297 → 317
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:28 → 67
      KRAB; KRAB box
      pfam13465
      Location:337 → 362
      zf-H2C2_2; Zinc-finger double domain

    4. XM_039106642.2 → XP_038962570.1  zinc finger protein 120 isoform X3

      Conserved Domains (2) summary
      sd00017
      Location:101 → 121
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:27 → 68
      KRAB; KRAB box

    5. XM_006235193.5 → XP_006235255.1  zinc finger protein 120 isoform X5

      Conserved Domains (2) summary
      smart00349
      Location:28 → 75
      KRAB; krueppel associated box
      pfam01352
      Location:28 → 67
      KRAB; KRAB box

    RNA

    1. XR_005502578.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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