Plxdc1 plexin domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Plxdc1provided by RGD
Official Full Name: plexin domain containing 1provided by RGD
Primary source: RGD:1307496
See related: EnsemblRapid:ENSRNOG00000021536 AllianceGenome:RGD:1307496
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Tem7; Arl12
Summary: Involved in spinal cord development. Located in dendrite and neuronal cell body. Orthologous to human PLXDC1 (plexin domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 31.7), Brain (RPKM 21.1) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q31

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (83418837..83478451, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (82922499..82982124, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (85871122..85938085, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

TEM7 mRNA expression was localized to the neuronal population of the sensory ganglion. Immunohistochemical analysis on TEM protein with specific antibodies further supported the spatial expression patterns of TEM7 mRNA in the DRG.
Title: Expression of tumor endothelial marker 7 mRNA and protein in the dorsal root ganglion neurons of the rat.

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General gene information

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Markers

D2S2154 (e-PCR)
- UniSTS:26461

RH130586 (e-PCR)
- UniSTS:213870

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in spinal cord development	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
part_of receptor complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: plexin domain-containing protein 1

Names: ADP-ribosylation factor-like 12; tumor endothelial marker7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.