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    Abcg3l3 ATP-binding cassette, subfamily G (WHITE), member 3-like 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305142, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Abcg3l3provided by RGD
    Official Full Name
    ATP-binding cassette, subfamily G (WHITE), member 3-like 3provided by RGD
    Primary source
    RGD:1564709
    See related
    EnsemblRapid:ENSRNOG00000069246 AllianceGenome:RGD:1564709
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564709
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity; efflux transmembrane transporter activity; and riboflavin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 81.6), Lung (RPKM 65.4) and 9 other tissues See more
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    Genomic context

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    See Abcg3l3 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (5148826..5196890)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (4844161..4892194)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (5733361..6104164)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, subfamily G (WHITE), member 3 Neighboring gene small nucleolar RNA U3 Neighboring gene uncharacterized LOC120096558 Neighboring gene zinc finger protein 658-like 1 Neighboring gene uncharacterized LOC134481698 Neighboring gene zinc finger protein 950 like 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables efflux transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables riboflavin transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in riboflavin transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ATP-binding cassette, sub-family G (WHITE), member 3 family member

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107205.1 → NP_001100675.1  ATP-binding cassette, sub-family G (WHITE), member 3 family member

      See identical proteins and their annotated locations for NP_001100675.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474022
      UniProtKB/TrEMBL
      A0A8I6A653, A0A8I6ACK9, A6K5Q8
      Related
      ENSRNOP00000089408.1, ENSRNOT00000093929.2
      Conserved Domains (1) summary
      TIGR00955
      Location:64 → 644
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      5148826..5196890
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091819.2 → XP_038947747.1  ATP-binding cassette, sub-family G (WHITE), member 3 family member isoform X2

      Conserved Domains (1) summary
      TIGR00955
      Location:64 → 487
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein

    2. XM_063273045.1 → XP_063129115.1  ATP-binding cassette, sub-family G (WHITE), member 3 family member isoform X1

    3. XM_039091817.2 → XP_038947745.1  ATP-binding cassette, sub-family G (WHITE), member 3 family member isoform X1

      Conserved Domains (1) summary
      TIGR00955
      Location:3 → 514
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    Nucleotide Protein Strain
    Heading Accession and Version

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