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    Pdia2 protein disulfide isomerase family A, member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287164, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pdia2provided by RGD
    Official Full Name
    protein disulfide isomerase family A, member 2provided by RGD
    Primary source
    RGD:1305164
    See related
    EnsemblRapid:ENSRNOG00000063310 AllianceGenome:RGD:1305164
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pdip
    Summary
    Predicted to enable protein-disulfide reductase activity. Predicted to act upstream of or within platelet aggregation. Predicted to be located in endoplasmic reticulum lumen. Orthologous to human PDIA2 (protein disulfide isomerase family A member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Pdia2 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15720301..15723386, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (15215824..15218937, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L28 Neighboring gene axin 1 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene Rho GDP dissociation inhibitor gamma Neighboring gene regulator of G-protein signaling 11

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within platelet aggregation  
    involved_in protein folding  
    involved_in response to endoplasmic reticulum stress  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum  
    located_in endoplasmic reticulum lumen  

    General protein information

    Preferred Names
    protein disulfide-isomerase A2
    Names
    protein disulfide isomerase associated 2
    protein disulfide isomerase, pancreatic
    NP_001099245.2
    XP_038941296.1
    XP_038941297.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105775.2NP_001099245.2  protein disulfide-isomerase A2 precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6A0T0
      Related
      ENSRNOP00000085020.1, ENSRNOT00000099303.2
      Conserved Domains (1) summary
      TIGR01130
      Location:45506
      ER_PDI_fam; protein disulfide isomerase, eukaryotic

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15720301..15723386 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085368.2XP_038941296.1  protein disulfide-isomerase A2 isoform X1

      Conserved Domains (1) summary
      TIGR01130
      Location:45440
      ER_PDI_fam; protein disulfide isomerase, eukaryotic
    2. XM_039085369.2XP_038941297.1  protein disulfide-isomerase A2 isoform X2

      Conserved Domains (1) summary
      TIGR01130
      Location:1336
      ER_PDI_fam; protein disulfide isomerase, eukaryotic

    RNA

    1. XR_005489718.2 RNA Sequence

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