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    Mcemp1 mast cell-expressed membrane protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498128, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mcemp1provided by RGD
    Official Full Name
    mast cell-expressed membrane protein 1provided by RGD
    Primary source
    RGD:1565374
    See related
    EnsemblRapid:ENSRNOG00000028259 AllianceGenome:RGD:1565374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565374
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in membrane. Orthologous to human MCEMP1 (mast cell expressed membrane protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 71.1), Spleen (RPKM 29.2) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mcemp1 in Genome Data Viewer
    Location:
    12p12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (6519709..6523880)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (1721781..1727350)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (2211970..2217005)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene syntaxin binding protein 2 Neighboring gene resistin Neighboring gene foxo1-corepressor-like Neighboring gene trafficking protein particle complex subunit 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke. Jian R, et al. J Cell Biochem, 2019 Oct. PMID 31104315

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke.
      Title: Lentiviral-mediated silencing of mast cell-expressed membrane protein 1 promotes angiogenesis of rats with cerebral ischemic stroke.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mast cell-expressed membrane protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134602.2 → NP_001128074.2  mast cell-expressed membrane protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6KQ30

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      6519709..6523880
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017598421.3 → XP_017453910.1  mast cell-expressed membrane protein 1 isoform X1

    2. XM_039089664.2 → XP_038945592.1  mast cell-expressed membrane protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K062, A6KQ30
      Related
      ENSRNOP00000098741.1, ENSRNOT00000139444.1
      Conserved Domains (1) summary
      pfam03954
      Location:91 → 172
      Lectin_N; Hepatic lectin, N-terminal domain

    3. XM_039089666.2 → XP_038945594.1  mast cell-expressed membrane protein 1 isoform X3

      UniProtKB/TrEMBL
      A6KQ30
      Related
      ENSRNOP00000030516.6, ENSRNOT00000031653.6
      Conserved Domains (1) summary
      pfam03954
      Location:81 → 162
      Lectin_N; Hepatic lectin, N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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