Adprh ADP-ribosylarginine hydrolase [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Adprhprovided by RGD
Official Full Name: ADP-ribosylarginine hydrolaseprovided by RGD
Primary source: RGD:2052
See related: EnsemblRapid:ENSRNOG00000027260 AllianceGenome:RGD:2052
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: ADPRHA
Summary: Enables ADP-ribosylarginine hydrolase activity. Involved in protein modification process. Located in extracellular space. Orthologous to human ADPRH (ADP-ribosylarginine hydrolase). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 142.9), Brain (RPKM 113.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 11q21

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (75805347..75811686)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (62299831..62306170)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (64861772..64868112)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ADP-ribosylarginine hydrolase activity	IDA Inferred from Direct Assay more info	PubMed
enables ADP-ribosylarginine hydrolase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables ADP-ribosylarginine hydrolase activity	ISO Inferred from Sequence Orthology more info
enables magnesium ion binding	ISO Inferred from Sequence Orthology more info
enables magnesium ion binding	ISS Inferred from Sequence or Structural Similarity more info
enables potassium ion binding	ISO Inferred from Sequence Orthology more info
enables potassium ion binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in protein de-ADP-ribosylation	ISO Inferred from Sequence Orthology more info
involved_in protein de-ADP-ribosylation	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein modification process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein modification process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: ADP-ribosylhydrolase ARH1

Names: ADP-ribose-L-arginine cleaving enzyme; [Protein ADP-ribosylarginine] hydrolase

NP_899154.2

EC 3.2.2.19

XP_006248422.1

EC 3.2.2.19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.