Asnsd1 asparagine synthetase domain containing 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Asnsd1provided by RGD
Official Full Name: asparagine synthetase domain containing 1provided by RGD
Primary source: RGD:1306332
See related: EnsemblRapid:ENSRNOG00000003942 AllianceGenome:RGD:1306332
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1306332
Summary: Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process and skeletal muscle tissue development. Predicted to act upstream of or within adipose tissue development; skeletal muscle organ development; and transdifferentiation. Orthologous to human ASNSD1 (asparagine synthetase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 350.0), Muscle (RPKM 221.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 9q22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (55618799..55631064)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (48126808..48139073)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (52988042..53009054)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables asparagine synthase (glutamine-hydrolyzing) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within adipose tissue development	ISO Inferred from Sequence Orthology more info
involved_in asparagine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within muscle organ development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within skeletal muscle organ development	ISO Inferred from Sequence Orthology more info
involved_in skeletal muscle tissue development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within skeletal muscle tissue development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within transdifferentiation	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: asparagine synthetase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106763.1 → NP_001100233.1 asparagine synthetase domain-containing protein 1

See identical proteins and their annotated locations for NP_001100233.1

Status: PROVISIONAL

Source sequence(s)

CH473965

UniProtKB/TrEMBL

A6INT9, D3ZWR3

Related

ENSRNOP00000056002.2, ENSRNOT00000059233.4

Conserved Domains (2) summary

cd01991
Location:322 → 603

Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...

cd03766
Location:1 → 179

Gn_AT_II_novel; This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is ...