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    Ints9 integrator complex subunit 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 290322, updated on 9-Dec-2024

    Summary

    Symbol
    Ints9provided by RGD
    Full Name
    integrator complex subunit 9provided by RGD
    Primary source
    RGD:1311539
    See related
    EnsemblRapid:ENSRNOG00000013459 AllianceGenome:RGD:1311539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311539
    Summary
    Predicted to be involved in negative regulation of transforming growth factor beta receptor signaling pathway and snRNA 3'-end processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of integrator complex. Orthologous to human INTS9 (integrator complex subunit 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 78.2), Thymus (RPKM 72.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ints9 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (43376235..43460549)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (39200541..39284858)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (48326728..48413792)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 13B Neighboring gene homeobox containing 1 Neighboring gene high mobility group nucleosomal binding domain 4, pseudogene 7 Neighboring gene uncharacterized LOC134482133 Neighboring gene exostosin-like glycosyltransferase 3 Neighboring gene H/ACA ribonucleoprotein complex subunit 3-like Neighboring gene frizzled class receptor 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in snRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in snRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of integrator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of integrator complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    integrator complex subunit 9

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402259.1NP_001389188.1  integrator complex subunit 9

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000015
      UniProtKB/TrEMBL
      A0A8I6A9P4, F1M365
      Related
      ENSRNOP00000088568.2, ENSRNOT00000096924.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      43376235..43460549
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274137.1XP_063130207.1  integrator complex subunit 9 isoform X1

      UniProtKB/TrEMBL
      A6K6I8