Ninj2 ninjurin 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ninj2provided by RGD
Official Full Name: ninjurin 2provided by RGD
Primary source: RGD:620552
See related: AllianceGenome:RGD:620552
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in cell adhesion. Predicted to be located in plasma membrane. Orthologous to human NINJ2 (ninjurin 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 20.0), Testes (RPKM 10.3) and 7 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q42

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (154978660..155080860)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (153306439..153408618)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (152630464..152733631)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Spinal Ninjurin2 contributes to the neuropathic pain via NF-kappaB-mediated neuroinflammation in the spared sciatic nerve injury rats.
Title: Spinal Ninjurin2 contributes to the neuropathic pain via NF-κB-mediated neuroinflammation in the spared sciatic nerve injury rats.

Submit: New GeneRIF Correction

General gene information

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Markers

BI275338 (e-PCR)
- UniSTS:249628

RH133651 (e-PCR)
- UniSTS:216934

BF395779 (e-PCR)
- UniSTS:245406

BM385328 (e-PCR)
- UniSTS:261101

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
NOT enables membrane destabilizing activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info
NOT involved_in cytolysis	ISO Inferred from Sequence Orthology more info
involved_in tissue regeneration	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ninjurin-2

Names: nerve injury-induced protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.