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    Zfp518b zinc finger protein 518B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498390, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp518bprovided by RGD
    Official Full Name
    zinc finger protein 518Bprovided by RGD
    Primary source
    RGD:1564150
    See related
    EnsemblRapid:ENSRNOG00000028534 AllianceGenome:RGD:1564150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564150
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF518B (zinc finger protein 518B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp518b in Genome Data Viewer
    Location:
    14q21
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (76333582..76352804)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (72121085..72140479)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (76853171..76872476)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene cytokine-dependent hematopoietic cell linker Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120096632 Neighboring gene U6 spliceosomal RNA Neighboring gene non-POU domain containing, octamer-binding, pseudogene 12 Neighboring gene ribonucleotide reductase M1, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 518B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432825.1 → NP_001419754.1  zinc finger protein 518B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A6IJS9, D4ABC6

    2. NM_001432826.1 → NP_001419755.1  zinc finger protein 518B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A6IJS9, D4ABC6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      76333582..76352804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017599488.3 → XP_017454977.1  zinc finger protein 518B isoform X1

      Related
      ENSRNOP00000097304.1, ENSRNOT00000106470.2
      Conserved Domains (2) summary
      sd00017
      Location:140 → 160
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:179 → 200
      zf-H2C2_2; Zinc-finger double domain

    2. XM_008770231.4 → XP_008768453.1  zinc finger protein 518B isoform X1

      Related
      ENSRNOP00000099511.1, ENSRNOT00000157678.1
      Conserved Domains (2) summary
      sd00017
      Location:140 → 160
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:179 → 200
      zf-H2C2_2; Zinc-finger double domain

    3. XM_039092820.1 → XP_038948748.1  zinc finger protein 518B isoform X2

      Conserved Domains (2) summary
      sd00017
      Location:140 → 160
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13909
      Location:167 → 189
      zf-H2C2_5; C2H2-type zinc-finger domain

    4. XM_039092821.2 → XP_038948749.1  zinc finger protein 518B isoform X3

      Conserved Domains (2) summary
      sd00017
      Location:140 → 160
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13909
      Location:167 → 189
      zf-H2C2_5; C2H2-type zinc-finger domain

    RNA

    1. XR_005493342.2 RNA Sequence

    2. XR_005493343.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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