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    Haus4 HAUS augmin-like complex, subunit 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305882, updated on 9-Dec-2024

    Summary

    Official Symbol
    Haus4provided by RGD
    Official Full Name
    HAUS augmin-like complex, subunit 4provided by RGD
    Primary source
    RGD:1305288
    See related
    EnsemblRapid:ENSRNOG00000039284 AllianceGenome:RGD:1305288
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305288
    Summary
    Predicted to enable microtubule minus-end binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in centrosome and mitotic spindle microtubule. Predicted to be part of HAUS complex. Orthologous to human HAUS4 (HAUS augmin like complex subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 118.2), Testes (RPKM 98.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Haus4 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (31964555..31976853, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (27994530..28006147, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33182139..33193880, complement)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene protein arginine methyltransferase 5 Neighboring gene transfer RNA arginine (anticodon ACG) 3 Neighboring gene ajuba LIM protein Neighboring gene similar to human chromosome 14 open reading frame 93

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables microtubule minus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in centrosome cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of HAUS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of HAUS complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    HAUS augmin-like complex subunit 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013995.1NP_001014017.1  HAUS augmin-like complex subunit 4

      See identical proteins and their annotated locations for NP_001014017.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079109
      UniProtKB/TrEMBL
      A0A8I6AFF1, A0A9K3Y7C0, F1LS46, Q6AYC0
      Related
      ENSRNOP00000016401.6, ENSRNOT00000016401.9
      Conserved Domains (1) summary
      pfam14735
      Location:126360
      HAUS4; HAUS augmin-like complex subunit 4

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      31964555..31976853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251955.4XP_006252017.1  HAUS augmin-like complex subunit 4 isoform X1

      See identical proteins and their annotated locations for XP_006252017.1

      UniProtKB/TrEMBL
      A0A8I6AFF1, A0A9K3Y7C0, F1LS46, Q6AYC0
      Conserved Domains (1) summary
      pfam14735
      Location:126360
      HAUS4; HAUS augmin-like complex subunit 4
    2. XM_006251956.5XP_006252018.1  HAUS augmin-like complex subunit 4 isoform X1

      See identical proteins and their annotated locations for XP_006252018.1

      UniProtKB/TrEMBL
      A0A8I6AFF1, A0A9K3Y7C0, F1LS46, Q6AYC0
      Conserved Domains (1) summary
      pfam14735
      Location:126360
      HAUS4; HAUS augmin-like complex subunit 4