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    Tsnax translin-associated factor X [ Rattus norvegicus (Norway rat) ]

    Gene ID: 64028, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tsnaxprovided by RGD
    Official Full Name
    translin-associated factor Xprovided by RGD
    Primary source
    RGD:621574
    See related
    EnsemblRapid:ENSRNOG00000049784 AllianceGenome:RGD:621574
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Trax
    Summary
    Enables A2A adenosine receptor binding activity. Contributes to sequence-specific DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in siRNA processing. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be part of endoribonuclease complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human TSNAX (translin associated factor X). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 296.2), Heart (RPKM 248.9) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tsnax in Genome Data Viewer
    Location:
    19q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (69873210..69887244)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (52975848..52989886)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (57771539..57785567)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene single stranded DNA binding protein 1, pseudogene 3 Neighboring gene uncharacterized LOC102549918 Neighboring gene large ribosomal subunit protein eL27-like Neighboring gene ribosomal protein S25, pseudogene 3 Neighboring gene DISC1 scaffold protein Neighboring gene uncharacterized LOC134483407

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC93125

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables A2A adenosine receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA endonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in siRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of endoribonuclease complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    translin-associated protein X

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022262.3NP_071598.1  translin-associated protein X

      See identical proteins and their annotated locations for NP_071598.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081715
      UniProtKB/Swiss-Prot
      Q9JHB5
      UniProtKB/TrEMBL
      A6KJ28
      Related
      ENSRNOP00000063911.1, ENSRNOT00000071827.4
      Conserved Domains (1) summary
      cl00957
      Location:42256
      Translin-like; Translin and translin-associated factor-X (TRAX)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      69873210..69887244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)